血清睾酮检测

Assays of Serum Testosterone.

作者信息

Herati Amin S, Cengiz Cenk, Lamb Dolores J

机构信息

Scott Department of Urology, Center for Reproductive Medicine, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.

Scott Department of Urology, Center for Reproductive Medicine, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.

出版信息

Urol Clin North Am. 2016 May;43(2):177-84. doi: 10.1016/j.ucl.2016.01.003.

DOI:10.1016/j.ucl.2016.01.003

PMID:27132574

Abstract

The diagnosis of male hypogonadism depends on an assessment of the clinical signs and symptoms of hypogonadism and serum testosterone level. Current clinical laboratory testosterone assay platforms include immunoassays and mass spectrometry. Despite significant advances to improve the accuracy and precision of the currently available assays, limited comparability exists between assays at the lower and upper extremes of the testosterone range. Because of this lack of comparability, there is no current gold standard assay for the assessment of total testosterone levels.

摘要

男性性腺功能减退的诊断取决于对性腺功能减退的临床体征和症状以及血清睾酮水平的评估。当前临床实验室的睾酮检测平台包括免疫测定法和质谱分析法。尽管在提高现有检测方法的准确性和精密度方面取得了重大进展，但在睾酮范围的下限和上限处，各检测方法之间的可比性有限。由于缺乏这种可比性，目前尚无用于评估总睾酮水平的金标准检测方法。