高分辨率T1加权三维梯度回波（LAVA）与两点法狄克逊脂肪/水分离（FLEX）对比T1加权快速自旋回波（FSE）在前列腺癌（PCa）中的应用
Comparison of high-resolution T1W 3D GRE (LAVA) with 2-point Dixon fat/water separation (FLEX) to T1W fast spin echo (FSE) in prostate cancer (PCa).
作者信息
Samji Karim, Alrashed Abdulmohsen, Shabana Wael M, McInnes Matthew Df, Bayram Ersin, Schieda Nicola
机构信息
Department of Diagnostic Imaging, The Ottawa Hospital, 1053 Carling Avenue, Ottawa, ON, Canada K1Y 4E9.
Global MR Applications and Workflow, GE Healthcare, Houston, TX, USA.
出版信息
Clin Imaging. 2016 May-Jun;40(3):407-13. doi: 10.1016/j.clinimag.2015.11.023. Epub 2015 Dec 3.
PURPOSE
To compare T1-weighted (T1W) fast spin echo (FSE) to T1W 3-dimensional gradient recalled echo (LAVA) with fat water separation (FLEX) in prostate cancer (PCa).
METHODOLOGY
With institutional review board waiver, 39 patients underwent 3-T magnetic resonance imaging including T1W LAVA FLEX (157s)/T1W FSE (316s). Two radiologists assessed (a) image quality/sharpness, (b) presence/severity of artifacts, and (c) skeletal (N=22)/nodal (N=9) metastases. Results were compared using Wilcoxon signed-rank test/receiver operator characteristic analysis.
RESULTS
With T1W LAVA FLEX, image quality/sharpness improved (P<.001) with less motion (P=.002-.03) and no difference in phase-encoding artifact (P>.05). One patient had moderate fat/water swap. Detection of skeletal metastases was unchanged (P>.05) and nodal metastases either improved (P=.002) or were comparable (P=.16) using T1W LAVA FLEX.
CONCLUSION
T1W LAVA FLEX improves image quality, lessens motion artifact, and is comparable or improves detection of metastases in PCa with reduction in acquisition time.
目的
比较T1加权（T1W）快速自旋回波（FSE）序列与T1W三维梯度回波（LAVA）序列联合脂肪水分离（FLEX）技术在前列腺癌（PCa）中的应用。
方法
在获得机构审查委员会豁免的情况下，39例患者接受了3-T磁共振成像检查，包括T1W LAVA FLEX序列（157秒）/T1W FSE序列（316秒）。两名放射科医生评估（a）图像质量/清晰度，（b）伪影的存在/严重程度，以及（c）骨骼转移（N=22）/淋巴结转移（N=9）情况。使用Wilcoxon符号秩检验/受试者操作特征分析比较结果。
结果
采用T1W LAVA FLEX序列时，图像质量/清晰度有所提高（P<.001），运动伪影减少（P=.002-.03），相位编码伪影无差异（P>.05）。1例患者出现中度脂肪/水交换。骨骼转移的检测情况未变（P>.05），使用T1W LAVA FLEX序列时，淋巴结转移的检测情况有所改善（P=.002）或相当（P=.16）。
结论
T1W LAVA FLEX序列可提高图像质量，减少运动伪影，在前列腺癌中对转移灶的检测效果相当或有所改善，同时采集时间缩短。
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