64层螺旋CT评估心外膜脂肪组织与冠状动脉狭窄严重程度的相关性
Correlation between epicardial adipose tissue and severity of coronary artery stenosis evaluated by 64-MDCT.
作者信息
Yang Chunying, Li Liang, Zha Yunfei, Peng Zhoufeng
机构信息
Department of Radiology, the Huaihe Hospital of Henan University, Henan, Kaifeng, 475000, PR China; Department of Radiology, the People's Hospital of Wuhan University, Wuhan, 430060, PR China.
Department of Radiology, the Huaihe Hospital of Henan University, Henan, Kaifeng, 475000, PR China.
出版信息
Clin Imaging. 2016 May-Jun;40(3):477-80. doi: 10.1016/j.clinimag.2015.12.003. Epub 2015 Dec 18.
PURPOSE
The purpose was to investigate the correlation between epicardial adipose tissue (EAT) thickness, EAT volume, and severity of coronary artery stenosis.
METHODS
We retrospectively enrolled 188 patients that underwent coronary computed tomography (CT) angiography for clinically suspected coronary artery disease using 64-MDCT. Images were reconstructed using a retrospective electrocardiogram-gated algorithm with 0.625-mm-thick sections. EAT thickness and volume were calculated.
RESULTS
The coronary CT angiography showed 106 patients who had coronary artery pathology (178 lesions), 21 patients with moderate stenosis (27 lesions), 12 patients with severe stenosis (18 lesions), and 6 patients with complete occlusion (8 lesions). EAT thickness, EAT volume, and Gensini score were statistically different among groups (FT=32.306, FV=27.743, F=110.483, P=.000). Pearson correlation analysis showed that Gensini score had significantly positive correlation with EAT thickness and volume, respectively.
CONCLUSION
EAT thickness and volume demonstrated a positive correlation with severity of coronary artery stenosis.
目的
本研究旨在探讨心外膜脂肪组织（EAT）厚度、EAT体积与冠状动脉狭窄严重程度之间的相关性。
方法
我们回顾性纳入了188例因临床怀疑冠心病而接受64层螺旋CT冠状动脉造影检查的患者。使用回顾性心电图门控算法重建图像，层厚0.625mm。计算EAT厚度和体积。
结果
冠状动脉CT血管造影显示，106例患者存在冠状动脉病变（178处病变），21例患者为中度狭窄（27处病变），12例患者为重度狭窄（18处病变），6例患者完全闭塞（8处病变）。EAT厚度、EAT体积和Gensini评分在各组间差异有统计学意义（FT=32.306，FV=27.743，F=110.483，P=0.000）。Pearson相关分析显示，Gensini评分分别与EAT厚度和体积呈显著正相关。
结论
EAT厚度和体积与冠状动脉狭窄严重程度呈正相关。
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