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双侧疼痛性眼肌麻痹:一例疑似托洛萨-亨特综合征病例

Bilateral Painful Ophthalmoplegia: A Case of Assumed Tolosa-Hunt Syndrome.

作者信息

Kastirr Ilko, Kamusella Peter, Andresen Reimer

机构信息

Medical Assistant, Institute of Diagnostic and Interventional Radiology/Neuroradiology, Westküstenklinikum Heide, Academic Teaching Hospital of the Universities of Kiel , Lübeck and Hamburg, Germany .

Medical Specialist, Institute of Diagnostic and Interventional Radiology/Neuroradiology, Westküstenklinikum Heide, Academic Teaching Hospital of the Universities of Kiel , Lübeck and Hamburg, Germany .

出版信息

J Clin Diagn Res. 2016 Mar;10(3):TD16-7. doi: 10.7860/JCDR/2016/16703.7496. Epub 2016 Mar 1.

Abstract

We present the case of a man of 47 years with vertical and horizontal paresis of view combined with periorbital pain that developed initially on the right side but extended after 3-4 days to the left. Gadolinum uptaking tissue in the cavernous sinus was shown by MRI of the orbital region in the T1 spin echo sequence with fat saturation (SEfs) with a slice thickness of 2 mm. As no other abnormalities were found and the pain resolved within 72 hours of treatment with cortison a bilateral Tolosa-Hunt Syndrome (THS) was assumed. THS is an uncommon cause for Painful Ophthalmoglegia (PO) and only few cases of bilateral appearance have been reported. Even though the diagnostic criteria for THS oblige unilateral symptoms we suggest that in patients with bilateral PO THS should not be excluded as a differential diagnosis. Further more when using MRI to detect granulomatous tissue in the orbital region the chosen sequence should be T1 SEfs and slice thickness should possibly be as low as 2 mm, as granulomas are often no larger than 1-2 mm.

摘要

我们报告一例47岁男性病例,其存在垂直和水平视野麻痹,并伴有眶周疼痛,疼痛最初出现在右侧,但在3 - 4天后扩展至左侧。眼眶区域的MRI在T1自旋回波序列脂肪抑制(SEfs)、层厚2mm的情况下显示海绵窦内有钆摄取组织。由于未发现其他异常,且疼痛在使用皮质类固醇治疗72小时内缓解,故推测为双侧托洛萨 - 亨特综合征(THS)。THS是引起疼痛性眼肌麻痹(PO)的罕见原因,仅有少数双侧发病的病例报道。尽管THS的诊断标准要求为单侧症状,但我们认为对于双侧PO患者,不应排除THS作为鉴别诊断。此外,当使用MRI检测眼眶区域的肉芽肿组织时,所选序列应为T1 SEfs,层厚可能低至2mm,因为肉芽肿通常不大于1 - 2mm。

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