EaStCHEM School of Chemistry, University of St. Andrews, St. Andrews, Fife, KY16 9ST, UK.
Angew Chem Int Ed Engl. 2016 Jun 13;55(25):7034-6. doi: 10.1002/anie.201602891. Epub 2016 May 2.
Knitting: Recently Antonchick and Manna described a unique annulation that knits together three acetophenones to construct cyclopropanes. The cascade is mediated by organocopper and free radical species, and amounts to the first known [1+1+1] cyclotrimerization. It works well for ketones having electron-deficient or electron-rich substituents in their aryl rings. DTBP=di-tert-butylperoxide.
最近 Antonchick 和 Manna 描述了一种独特的环化反应,它将三个苯乙酮编织在一起形成环丙烷。该级联反应由有机铜和自由基物种介导,是已知的第一个[1+1+1]环三聚反应。它适用于芳环上具有缺电子或富电子取代基的酮。DTBP=二叔丁基过氧化物。