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β-磷酸三钙植入物在空鼻综合征外科治疗中的应用

ß-Tricalcium Phosphate Implants in the Surgical Treatment of Empty Nose Syndrome.

作者信息

Bastier Pierre-Louis, Fierens Sylvestre, Champel Sylvain, Ribadeau-Dumas Alix, de Gabory Ludovic

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital of Bordeaux, Centre F-X Michelet, Bordeaux, France.

Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital of Bordeaux, Centre F-X Michelet, Bordeaux, France

出版信息

Otolaryngol Head Neck Surg. 2016 Sep;155(3):514-7. doi: 10.1177/0194599816644908. Epub 2016 May 3.

Abstract

The objective of this study was to assess the efficacy and morbidity of a β-tricalcium phosphate implant in the treatment of empty nose syndrome after turbinectomy. Only patients with a history of inferior turbinectomy and a complaint of permanent paradoxical nasal obstruction were included. β-Tricalcium phosphate ceramic implants were implanted under the mucoperiosteal plane of the lateral nasal wall to replace the head of the inferior turbinate. Symptoms and quality of life were assessed by 2 questionnaires: the Nasal Obstruction Symptom Evaluation and Rhinosinusitis Quality of Life. Fourteen patients were included. The mean follow-up was 19.4 ± 13.4 months. Scores for the Nasal Obstruction Symptom Evaluation and Rhinosinusitis Quality of Life (frequency, bothersomeness, and impact) significantly improved after surgery (respectively, 73.9 ± 21.8 to 34.6 ± 28.6, 44.6 ± 17.1 to 34.8 ± 20.3, 43.6 ± 22.4 to 70.7 ± 21.5, and 59.9 ± 21.1 to 27.2 ± 25.3; P < .05). The use of ß-tricalcium phosphate seems efficient to repair empty nose syndrome by endonasal microplasty and shows a low complication rate.

摘要

本研究的目的是评估β-磷酸三钙植入物在治疗鼻甲切除术后空鼻综合征中的疗效和发病率。仅纳入有下鼻甲切除术史且主诉永久性矛盾性鼻阻塞的患者。将β-磷酸三钙陶瓷植入物植入鼻侧壁的粘骨膜平面下,以替代下鼻甲头部。通过2份问卷评估症状和生活质量:鼻阻塞症状评估问卷和鼻窦炎生活质量问卷。共纳入14例患者。平均随访时间为19.4±13.4个月。术后鼻阻塞症状评估问卷和鼻窦炎生活质量问卷(频率、困扰程度和影响)的评分显著改善(分别从73.9±21.8降至34.6±28.6、从44.6±17.1降至34.8±20.3、从43.6±22.4升至70.7±21.5、从59.9±21.1降至27.2±25.3;P<0.05)。使用β-磷酸三钙通过鼻内微整形修复空鼻综合征似乎有效,且并发症发生率低。

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