大鼠血清中性别影响酯酶（ESSI）的重新检测

Re-examination on the sex-influenced esterase (ESSI) in rat serum.

作者信息

Nikaido H, Hayakawa J

机构信息

Institute for Experimental Animals, School of Medicine, Kanazawa University, Japan.

出版信息

Jikken Dobutsu. 1989 Jan;38(1):41-6. doi: 10.1538/expanim1978.38.1_41.

DOI:10.1538/expanim1978.38.1_41

PMID:2714376

Abstract

The sex-limitation of sex-influenced esterase (ESSI) in serum of rats carrying Es-Sia allele was re-examined. ESSI was detected in immature males and females, and orchiectomized rats as well as mature females whereas ESSI in normal males rapidly disappeared with puberty. The rats orchiectomized at weaning temporarily lost ESSI around the age of sexual maturation, thereafter, ESSI reappeared. When orchiectomized rats were administered testosterone, synthesis of ESSI was suppressed as in normal adult males. Effect of ovariectomy was not recognized. The exceptional strain named SI 3 of which normal mature males have a significant level of ESSI has been established, although the level in the males is lower than that in the females of the same strain.

摘要

对携带Es-Sia等位基因大鼠血清中受性别影响的酯酶（ESSI）的性别限制进行了重新研究。在未成熟的雄性和雌性大鼠、去势大鼠以及成熟雌性大鼠中均检测到了ESSI，而正常雄性大鼠中的ESSI在青春期时迅速消失。断奶时去势的大鼠在性成熟年龄左右暂时失去了ESSI，此后，ESSI又重新出现。当给去势大鼠注射睾酮时，ESSI的合成如同正常成年雄性大鼠一样受到抑制。未观察到卵巢切除的影响。已经培育出了名为SI 3的特殊品系，该品系正常成熟雄性大鼠具有显著水平的ESSI，尽管雄性大鼠中的该水平低于同一品系雌性大鼠中的水平。