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针灸治疗颈部疾病。

Acupuncture for neck disorders.

作者信息

Trinh Kien, Graham Nadine, Irnich Dominik, Cameron Ian D, Forget Mario

机构信息

DeGroote School of Medicine, Office of MD Admissions, McMaster University, 1200 Main Street West, MDCL-3112, Hamilton, ON, Canada, L8N 3Z5.

出版信息

Cochrane Database Syst Rev. 2016 May 4(5):CD004870. doi: 10.1002/14651858.CD004870.pub4.

Abstract

BACKGROUND

Neck pain is one of the three most frequently reported complaints of the musculoskeletal system. Treatments for neck pain are varied, as are perceptions of benefit. Acupuncture has been used as an alternative to more conventional treatment for musculoskeletal pain. This review summarises the most current scientific evidence on the effectiveness of acupuncture for acute, subacute and chronic neck pain. This update replaces our 2006 Cochrane review update on this topic.

OBJECTIVES

To determine the effects of acupuncture for adults with neck pain, with focus on pain relief, disability or functional measures, patient satisfaction and global perceived effect.

SEARCH METHODS

We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, the Manual, Alternative and Natural Therapy Index System (MANTIS), the Cumulative Index to Nursing and Allied Health Literature (CINAHL) and the Index to Chiropractic Literature (ICL) from their beginning to August 2015. We searched reference lists, two trial registers and the acupuncture database Traditional Chinese Medical Literature Analysis and Retrieval System (TCMLARS) in China to 2005.

SELECTION CRITERIA

We included published trials that used random assignment to intervention groups, in full text or abstract form. We excluded quasi-randomised controlled trials (RCTs).

DATA COLLECTION AND ANALYSIS

Two review authors made independent decisions for each step of the review: article inclusion, data abstraction and assessment of quality of trial methods. We assessed study quality by using the Cochrane Back Review Group 'Risk of bias' tool. We used consensus to resolve disagreements, and when clinical heterogeneity was absent, we combined studies by using random-effects meta-analysis models.

MAIN RESULTS

Of the 27 included studies, three represented individuals with whiplash-associated disorders (WADs) ranging from acute to chronic (205 participants), five explored chronic myofascial neck pain (186 participants), five chronic pain due to arthritic changes (542 participants), six chronic non-specific neck pain (4011 participants), two neck pain with radicular signs (43 participants) and six subacute or chronic mechanical neck pain (5111 participants).For mechanical neck pain, we found that acupuncture is beneficial at immediate-term follow-up compared with sham acupuncture for pain intensity; at short-term follow-up compared with sham or inactive treatment for pain intensity; at short-term follow-up compared with sham treatment for disability; and at short-term follow-up compared with wait-list control for pain intensity and neck disability improvement. Statistical pooling was appropriate for acupuncture compared with sham for short-term outcomes due to statistical homogeneity (P value = 0.83; I(2) = 20%). Results of the meta-analysis favoured acupuncture (standardised mean difference (SMD) -0.23, 95% confidence interval (CI) -0.20 to -0.07; P value = 0.0006). This effect does not seem sustainable over the long term. Whether subsequent repeated sessions would be successful was not examined by investigators in our primary studies.Acupuncture appears to be a safe treatment modality, as adverse effects are minor. Reported adverse effects include increased pain, bruising, fainting, worsening of symptoms, local swelling and dizziness. These studies reported no life-threatening adverse effects and found that acupuncture treatments were cost-effective.Since the time of our previous review, the quality of RCTs has improved, and we have assessed many of them as having low risk of bias. However, few large trials have provided high-quality evidence.

AUTHORS' CONCLUSIONS: Moderate-quality evidence suggests that acupuncture relieves pain better than sham acupuncture, as measured at completion of treatment and at short-term follow-up, and that those who received acupuncture report less pain and disability at short-term follow-up than those on a wait-list. Moderate-quality evidence also indicates that acupuncture is more effective than inactive treatment for relieving pain at short-term follow-up.

摘要

背景

颈部疼痛是肌肉骨骼系统最常报告的三大症状之一。颈部疼痛的治疗方法多种多样,对治疗效果的认知也各不相同。针灸已被用作治疗肌肉骨骼疼痛的一种替代传统疗法。本综述总结了关于针灸治疗急性、亚急性和慢性颈部疼痛有效性的最新科学证据。本次更新取代了我们2006年关于该主题的Cochrane综述更新。

目的

确定针灸对颈部疼痛成人的影响,重点关注疼痛缓解、残疾或功能指标、患者满意度和整体感知效果。

检索方法

我们检索了Cochrane对照试验中心注册库(CENTRAL)、MEDLINE、EMBASE、手册、替代和自然疗法索引系统(MANTIS)、护理及相关健康文献累积索引(CINAHL)以及整脊文献索引(ICL),检索时间范围从各数据库建库至2015年8月。我们还检索了参考文献列表、两个试验注册库以及中国的针灸数据库中国传统医学文献分析与检索系统(TCMLARS)至2005年。

选择标准

我们纳入了以全文或摘要形式发表的、采用随机分配至干预组的试验。我们排除了半随机对照试验(RCT)。

数据收集与分析

两位综述作者对综述的每个步骤做出独立决策:文章纳入、数据提取以及试验方法质量评估。我们使用Cochrane背部综述小组的“偏倚风险”工具评估研究质量。我们通过共识解决分歧,当不存在临床异质性时,我们使用随机效应荟萃分析模型合并研究。

主要结果

在纳入的27项研究中,3项研究涉及鞭打相关疾病(WADs)患者,范围从急性到慢性(205名参与者),5项研究探讨慢性肌筋膜性颈部疼痛(186名参与者),5项研究涉及关节炎改变导致的慢性疼痛(542名参与者),6项研究涉及慢性非特异性颈部疼痛(4011名参与者),2项研究涉及伴有神经根体征的颈部疼痛(43名参与者),6项研究涉及亚急性或慢性机械性颈部疼痛(5111名参与者)。对于机械性颈部疼痛,我们发现与假针灸相比,针灸在短期随访时对疼痛强度有益;与假针灸或非活性治疗相比,在短期随访时对疼痛强度有益;与假治疗相比,在短期随访时对残疾有益;与等待名单对照相比,在短期随访时对疼痛强度和颈部残疾改善有益。由于统计同质性(P值 = 0.83;I² = 20%),与假针灸相比,针灸的短期结果进行统计合并是合适的。荟萃分析结果支持针灸(标准化均数差(SMD)-0.23,95%置信区间(CI)-0.20至-0.07;P值 = 0.0006)。这种效果似乎在长期内不可持续。我们的主要研究中,研究人员未考察后续重复治疗是否会成功。针灸似乎是一种安全的治疗方式,因为不良反应较小。报告的不良反应包括疼痛加剧、瘀伤、昏厥、症状恶化、局部肿胀和头晕。这些研究报告没有危及生命的不良反应,并发现针灸治疗具有成本效益。自我们上次综述以来,RCT的质量有所提高,我们将其中许多研究评估为偏倚风险较低。然而,很少有大型试验提供高质量证据。

作者结论

中等质量的证据表明,在治疗结束时和短期随访时,针灸比假针灸能更好地缓解疼痛,并且接受针灸治疗的患者在短期随访时报告的疼痛和残疾程度低于等待名单上的患者。中等质量的证据还表明,在短期随访时,针灸比非活性治疗在缓解疼痛方面更有效。

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