Yang Chang-Sue, Chao Yu-Jang
Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC; Department of Ophthalmology, Taipei Medical University, Taipei, Taiwan, ROC.
Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2016 Aug;79(8):450-5. doi: 10.1016/j.jcma.2016.01.016. Epub 2016 Apr 15.
There is no general consensus on the optimal choice of intraocular lenses (IOLs) or fixation methods in eyes with inadequate capsular support. The purpose of this study was to determine the long-term safety, efficacy and refractive status of combined vitrectomy and transscleral suture fixation of posterior chamber (PC) IOLs in the management of posteriorly dislocated lenses in Taiwan.
We conducted a retrospective interventional study at our medical facility. The posteriorly dislocated crystalline lenses (or dislocated IOL) were removed with pars plana vitrectomy followed by transscleral suture fixation of PC IOLs at the same setting. Additionally, preexisting ocular condition, postoperative visual acuity (VA) and refraction were recorded.
Fifteen patients were enrolled for analysis, including traumatic posteriorly dislocated IOLs in seven cases, and traumatic posteriorly dislocated crystalline lenses or retained lens nuclei after cataract surgery in eight cases. The end result of our study showed that best-corrected VA of 6/12 or better was achieved in 13 patients (87%) after a mean 45 months follow-up. The mean VA significantly improved from 0.98 logarithm of the minimum angle of resolution (logMAR) at baseline to 0.14 logMAR at last follow-up (p < 0.01). The refractive status after suture fixation of PC IOL revealed a mean myopic shift of -1.18 ± 1.47 D from the predicted spherical equivalent. Overall, most complications were minor. Ciliary body hemorrhage occurred during operation in one case and was cleared without visual compromise. Erosion of prolene suture through conjunctiva was noted in three patients. Elevated intraocular pressure was well controlled by topical antiglaucoma medications in three cases. No suture breakage or IOL dislocation was noted in any of the patients. There were no serious adverse events of retinal detachment, corneal compromise, or endophthalmitis in any of the patients.
Our data showed that use of combined vitrectomy and transscleral suture fixation of PC IOLs is a safe and efficient technique to correct aphakia in eyes without adequate capsular support. Our study demonstrated good long-term visual outcome with only minor complications. Furthermore, we recommend that the IOL power should be adjusted 1.00 D less for transscleral suture fixation.
对于囊袋支撑不足的眼睛,人工晶状体(IOL)的最佳选择或固定方法尚无普遍共识。本研究的目的是确定在台湾,玻璃体切除术联合后房型人工晶状体经巩膜缝线固定术治疗晶状体后脱位的长期安全性、有效性和屈光状态。
我们在医疗机构进行了一项回顾性干预研究。通过平坦部玻璃体切除术切除晶状体后脱位的晶状体(或脱位的人工晶状体),然后在同一手术中进行后房型人工晶状体的经巩膜缝线固定。此外,记录术前眼部情况、术后视力(VA)和屈光情况。
纳入15例患者进行分析,其中7例为外伤性人工晶状体后脱位,8例为外伤性晶状体后脱位或白内障手术后残留晶状体核。我们的研究最终结果显示,平均随访45个月后,13例患者(87%)的最佳矫正视力达到6/12或更好。平均视力从基线时的最小分辨角对数(logMAR)0.98显著提高到最后随访时的0.14 logMAR(p < 0.01)。后房型人工晶状体缝线固定后的屈光状态显示,与预测的等效球镜度相比,平均近视偏移为-1.18±1.47 D。总体而言,大多数并发症较轻。1例患者术中发生睫状体出血,出血清除后视力未受影响。3例患者出现普理灵缝线穿过结膜的情况。3例患者的眼压升高通过局部抗青光眼药物得到良好控制。所有患者均未发现缝线断裂或人工晶状体脱位。所有患者均未发生视网膜脱离、角膜损伤或眼内炎等严重不良事件。
我们的数据表明,玻璃体切除术联合后房型人工晶状体经巩膜缝线固定术是一种安全有效的技术,可用于矫正囊袋支撑不足的眼睛的无晶状体状态。我们的研究显示长期视觉效果良好,仅有轻微并发症。此外,我们建议经巩膜缝线固定时,人工晶状体的屈光度应减少1.00 D进行调整。