Gadhiya Satishkumar V, Hu Chunhua, Harding Wayne W
Department of Chemistry, Hunter College, City University of New York, 695 Park Avenue, New York 10065, USA; Ph.D. Program in Chemistry, The Graduate Center of The City University of New York, 365 5th Avenue, New York 10016, USA.
Molecular Design Institute, Department of Chemistry, New York University, 100 Washington Square, New York 10003, USA.
Tetrahedron Lett. 2016 May 11;57(19):2090-2092. doi: 10.1016/j.tetlet.2016.03.108.
A formal enantioselective synthesis of (-)-stepholidine that provides an alternative preparation of key lactone intermediate is described. The stereostructure of (-)-stepholidine prepared via this method was confirmed by x-ray diffraction.
描述了一种对映选择性合成(-)-千金藤啶碱的方法,该方法提供了关键内酯中间体的另一种制备方法。通过X射线衍射确认了通过该方法制备的(-)-千金藤啶碱的立体结构。