CellMiner 配套工具：一个交互式网络应用程序，用于探索 CellMiner NCI-60 数据。
CellMiner Companion: an interactive web application to explore CellMiner NCI-60 data.
机构信息
Department of Biological Sciences.
Department of Medicinal Chemistry and Molecular Pharmacology Purdue University Center for Cancer Research.
出版信息
Bioinformatics. 2016 Aug 1;32(15):2399-401. doi: 10.1093/bioinformatics/btw162. Epub 2016 Mar 25.
UNLABELLED
The NCI-60 human tumor cell line panel is an invaluable resource for cancer researchers, providing drug sensitivity, molecular and phenotypic data for a range of cancer types. CellMiner is a web resource that provides tools for the acquisition and analysis of quality-controlled NCI-60 data. CellMiner supports queries of up to 150 drugs or genes, but the output is an Excel file for each drug or gene. This output format makes it difficult for researchers to explore the data from large queries. CellMiner Companion is a web application that facilitates the exploration and visualization of output from CellMiner, further increasing the accessibility of NCI-60 data.
AVAILABILITY AND IMPLEMENTATION
The web application is freely accessible at https://pul-bioinformatics.shinyapps.io/CellMinerCompanion The R source code can be downloaded at https://github.com/pepascuzzi/CellMinerCompanion.git
CONTACT
SUPPLEMENTARY INFORMATION
Supplementary data are available at Bioinformatics online.
未标注
NCI-60 人类肿瘤细胞系面板是癌症研究人员的宝贵资源，为多种癌症类型提供药物敏感性、分子和表型数据。CellMiner 是一个网络资源，提供了用于获取和分析经过质量控制的 NCI-60 数据的工具。CellMiner 支持对多达 150 种药物或基因的查询，但输出结果是每个药物或基因的 Excel 文件。这种输出格式使得研究人员难以从大型查询中探索数据。CellMiner Companion 是一个网络应用程序，可方便地探索和可视化 CellMiner 的输出，进一步增加了 NCI-60 数据的可访问性。
可用性和实现
该网络应用程序可在 https://pul-bioinformatics.shinyapps.io/CellMinerCompanion 免费访问。R 源代码可在 https://github.com/pepascuzzi/CellMinerCompanion.git 下载。
联系人
补充信息
补充数据可在 Bioinformatics 在线获得。
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