成人经内镜注射葡聚糖凝胶/透明质酸治疗膀胱输尿管反流
Management of Vesicoureteral Reflux by Endoscopic Injection of Dextranomer/Hyaluronic Acid in Adults.
作者信息
Stark Timothy W, Lacy John M, Preston David M
机构信息
University of Kentucky College of Medicine, and Department of Urology, University of Kentucky, Lexington, KY.
Department of Urology, University of Kentucky College of Medicine, Lexington, KY.
出版信息
Rev Urol. 2016;18(1):46-50.
A 74-year-old man presented for evaluation after discovery of a left bladder-wall tumor. He underwent transurethral resection of bladder tumor (TURBT) operation for treatment of low-grade, Ta urothelial cancer of the bladder. The patient developed recurrent disease and returned to the operating room for repeat TURBT, circumcision, and administration of intravesical mitomycin C. The patient developed balanitis xerotica obliterans 4 years post-circumcision, requiring self-dilation with a catheter. He subsequently developed 3 consecutive episodes of left-sided pyelonephritis. Further investigation with voiding cystourethrogram (VCUG) revealed Grade 3, left-sided vesicoureteral reflux (VUR). Due to existing comorbidities, the patient elected treatment with endoscopic dextranomer/hyaluronic acid injection. A post-operative VCUG demonstrated complete resolution of left-sided VUR. This patient has remained symptom free for 8 months post-injection, with no episodes of pyelonephritis.
一名74岁男性在发现左膀胱壁肿瘤后前来接受评估。他接受了经尿道膀胱肿瘤切除术（TURBT），以治疗低度Ta期膀胱尿路上皮癌。患者疾病复发，返回手术室接受再次TURBT、包皮环切术，并膀胱内注射丝裂霉素C。患者在包皮环切术后4年出现闭塞性干燥性龟头炎，需要用导管进行自我扩张。随后，他连续3次发生左侧肾盂肾炎。通过排尿性膀胱尿道造影（VCUG）进一步检查发现3级左侧膀胱输尿管反流（VUR）。由于存在合并症，患者选择了内镜下注射葡聚糖omer/透明质酸进行治疗。术后VCUG显示左侧VUR完全缓解。该患者在注射后8个月一直无症状，没有肾盂肾炎发作。
Zotero 插件