Saigal Karnika, Dhawan Benu, Rawre Jyoti, Khanna Neena, Chaudhry Rama
Department of Microbiology, All Institute of Medical Sciences, New Delhi, India.
Department of Dermatology and Venereology, All Institute of Medical Sciences, New Delhi, India.
Indian J Pathol Microbiol. 2016 Apr-Jun;59(2):194-6. doi: 10.4103/0377-4929.182019.
Limited data are available on the prevalence of genital mycoplasmas and Chlamydia trachomatis (CT) among Indian patients with genital tract infections. The objectives of the study were to determine the prevalence of Ureaplasma urealyticum (UU), Mycoplasma hominis (MH), Mycoplasma genitalium (MG), and CT in patients with genital tract infections. The antimicrobial susceptibilities of UU and MH were also assessed. Endocervical swabs/urethral swabs and first void urine samples of patients (n = 164) were collected. UU and MH were detected by culture and multiplex polymerase chain reaction (PCR). MG and CT were identified by PCR. Ureaplasma isolates were further biotyped and serotyped. Antimicrobial susceptibility was done by microbroth dilution method. UU, MH, MG, and CT were detected in 15.2%, 5.4%, 1.2%, and 6% patients, respectively. Ureaplasma parvum serovar 3/14 was the most prevalent. All isolates of UU and MH were uniformly susceptible to doxycycline and josamycin. Routine screening for these pathogens and antimicrobial susceptibility testing is warranted to prevent sequel of infections and formulate treatment guidelines.
关于印度生殖道感染患者中生殖支原体和沙眼衣原体（CT）的流行情况，现有数据有限。本研究的目的是确定生殖道感染患者中解脲脲原体（UU）、人型支原体（MH）、生殖支原体（MG）和CT的流行情况。还评估了UU和MH的抗菌敏感性。收集了患者（n = 164）的宫颈拭子/尿道拭子和首次晨尿样本。通过培养和多重聚合酶链反应（PCR）检测UU和MH。通过PCR鉴定MG和CT。对解脲脲原体分离株进一步进行生物分型和血清分型。采用微量肉汤稀释法进行抗菌敏感性检测。UU、MH、MG和CT分别在15.2%、5.4%、1.2%和6%的患者中检测到。微小脲原体血清型3/14最为常见。所有UU和MH分离株对多西环素和交沙霉素均敏感。对这些病原体进行常规筛查和抗菌敏感性检测，对于预防感染后遗症和制定治疗指南是必要的。
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