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开展研究的障碍与促进因素——结直肠癌中心协调员的视角

[Obstacles and facilitators of conducting studies - the perspective of colorectal cancer centers' coordinators].

作者信息

Kowalski C, Ferencz J, Benz S, Post S, Seufferlein T, Stinner B, Penzes O, Wesselmann S

机构信息

Deutsche Krebsgesellschaft e.V., Berlin, Germany.

OnkoZert GmbH, Neu-Ulm, Germany.

出版信息

Z Gastroenterol. 2016 May;54(5):409-15. doi: 10.1055/s-0041-111633. Epub 2016 May 12.

Abstract

INTRODUCTION

Clinical trials and health services research are crucial pillars for improving patient care. This paper examines factors inhibiting and promoting the study activity and the knowledge and use of trial registries (e. g. DRKS, StudyBox) as an opportunity to learn about existing studies.

MATERIAL AND METHODS

The coordinators of 274 cancer center sites certified according to the requirements of the German Cancer Society were surveyed using a standardized online questionnaire. Data were analyzed using descriptive and bivariate statistics to identify associations with characteristics of the sites (e. g. patient volume, ownership, teaching status).

RESULTS

176 sites participated in the survey (64.2 %). The central obstacle to study participa-tion from the centers' view is the low number of existing studies. General knowledge of the population about studies was considered low. Trial registries are known to almost all respondents, but are rarely used.

DISCUSSION

The results of the survey suggest that comprehensive measures are needed to sustainably increase the study activity. These include, for example, better information about studies, for example through appropriate databases, and (industry-independent) research funding. One possible way to sensitize patients for studies could be the comprehensive education of the population about the purpose of studies.

摘要

引言

临床试验和卫生服务研究是改善患者护理的关键支柱。本文探讨了抑制和促进研究活动的因素,以及作为了解现有研究的一个契机,对试验注册库(如德国临床试验注册中心、StudyBox)的认知和使用情况。

材料与方法

使用标准化在线问卷对274个符合德国癌症协会要求认证的癌症中心站点的协调员进行了调查。采用描述性和双变量统计分析数据,以确定与站点特征(如患者数量、所有权、教学地位)的关联。

结果

176个站点参与了调查(64.2%)。从各中心的角度来看,参与研究的主要障碍是现有研究数量较少。认为公众对研究的总体认知较低。几乎所有受访者都知道试验注册库,但很少使用。

讨论

调查结果表明,需要采取综合措施来可持续地增加研究活动。这些措施包括,例如,通过适当的数据库更好地提供有关研究的信息,以及(独立于行业的)研究资金。让患者对研究产生兴趣的一种可能方法是对公众进行关于研究目的的全面教育。

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