Mohile Supriya G, Hurria Arti, Cohen Harvey J, Rowland Julia H, Leach Corinne R, Arora Neeraj K, Canin Beverly, Muss Hyman B, Magnuson Allison, Flannery Marie, Lowenstein Lisa, Allore Heather G, Mustian Karen M, Demark-Wahnefried Wendy, Extermann Martine, Ferrell Betty, Inouye Sharon K, Studenski Stephanie A, Dale William
Department of Medicine, University of Rochester, Rochester, New York.
Medical Oncology and Experimental Therapeutics, City of Hope National Medical Center, Duarte, California.
Cancer. 2016 Aug 15;122(16):2459-568. doi: 10.1002/cncr.30053. Epub 2016 May 12.
In May 2015, the Cancer and Aging Research Group, in collaboration with the National Cancer Institute and the National Institute on Aging through a U13 grant, convened a conference to identify research priorities to help design and implement intervention studies to improve the quality of life and survivorship of older, frailer adults with cancer. Conference attendees included researchers with multidisciplinary expertise and advocates. It was concluded that future intervention trials for older adults with cancer should: 1) rigorously test interventions to prevent the decline of or improve health status, especially interventions focused on optimizing physical performance, nutritional status, and cognition while undergoing cancer treatment; 2) use standardized care plans based on geriatric assessment findings to guide targeted interventions; and 3) incorporate the principles of geriatrics into survivorship care plans. Also highlighted was the need to integrate the expertise of interdisciplinary team members into geriatric oncology research, improve funding mechanisms to support geriatric oncology research, and disseminate high-impact results to the research and clinical community. In conjunction with the 2 prior U13 meetings, this conference provided the framework for future research to improve the evidence base for the clinical care of older adults with cancer. Cancer 2016;122:2459-68. © 2016 American Cancer Society.
2015年5月，癌症与衰老研究小组通过一项U13资助，与美国国立癌症研究所和美国国立衰老研究所合作，召开了一次会议，以确定研究重点，帮助设计和实施干预研究，从而改善患有癌症的体弱老年人的生活质量和生存期。与会者包括具有多学科专业知识的研究人员和倡导者。会议得出结论，未来针对患有癌症的老年人的干预试验应：1）严格测试预防健康状况下降或改善健康状况的干预措施，尤其是在癌症治疗期间侧重于优化身体机能、营养状况和认知的干预措施；2）使用基于老年评估结果的标准化护理计划来指导有针对性的干预措施；3）将老年医学原则纳入生存护理计划。会议还强调，需要将跨学科团队成员的专业知识整合到老年肿瘤学研究中，改善支持老年肿瘤学研究的资助机制，并向研究和临床界传播具有重大影响的研究成果。与之前的两次U13会议一起，本次会议为未来的研究提供了框架，以改善患有癌症的老年人临床护理的证据基础。《癌症》2016年；122：2459 - 68。© 2016美国癌症协会。
