Suppr超能文献

三叶机械心脏瓣膜旋转区域的时间分辨显微粒子图像测速技术

Time-Resolved Micro PIV in the Pivoting Area of the Triflo Mechanical Heart Valve.

作者信息

Vennemann Bernhard M, Rösgen Thomas, Carrel Thierry P, Obrist Dominik

机构信息

Institute of Fluid Dynamics, ETH Zürich, Sonneggstrasse 3, 8092, Zurich, Switzerland.

ARTORG Center, University of Bern, Bern, Switzerland.

出版信息

Cardiovasc Eng Technol. 2016 Sep;7(3):210-22. doi: 10.1007/s13239-016-0264-z. Epub 2016 May 13.

Abstract

The Lapeyre-Triflo FURTIVA valve aims at combining the favorable hemodynamics of bioprosthetic heart valves with the durability of mechanical heart valves (MHVs). The pivoting region of MHVs is hemodynamically of special interest as it may be a region of high shear stresses, combined with areas of flow stagnation. Here, platelets can be activated and may form a thrombus which in the most severe case can compromise leaflet mobility. In this study we set up an experiment to replicate the pulsatile flow in the aortic root and to study the flow in the pivoting region under physiological hemodynamic conditions (CO = 4.5 L/min / CO = 3.0 L/min, f = 60 BPM). It was found that the flow velocity in the pivoting region could reach values close to that of the bulk flow during systole. At the onset of diastole the three valve leaflets closed in a very synchronous manner within an average closing time of 55 ms which is much slower than what has been measured for traditional bileaflet MHVs. Hot spots for elevated viscous shear stresses were found at the flanges of the housing and the tips of the leaflet ears. Systolic VSS was maximal during mid-systole and reached levels of up to 40 Pa.

摘要

拉佩尔-特里弗洛FURTIVA瓣膜旨在将生物人工心脏瓣膜良好的血流动力学与机械心脏瓣膜(MHV)的耐用性相结合。MHV的枢转区域在血流动力学方面具有特殊意义,因为它可能是高剪切应力区域,同时存在血流停滞区域。在这里,血小板可能被激活并形成血栓,在最严重的情况下会影响瓣叶活动。在本研究中,我们建立了一个实验来复制主动脉根部的脉动血流,并研究生理血流动力学条件下(心输出量=4.5升/分钟/心输出量=3.0升/分钟,心率=60次/分钟)枢转区域的血流情况。研究发现,枢转区域的血流速度在收缩期可接近总体血流速度。在舒张期开始时,三个瓣叶以非常同步的方式关闭,平均关闭时间为55毫秒,这比传统双叶MHV的测量值要慢得多。在瓣膜外壳的边缘和瓣叶耳部的尖端发现了粘性剪切应力升高的热点区域。收缩期粘性剪切应力在收缩中期最大,可达40帕。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验