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面部外恶性雀斑样痣:14例报告及文献综述。

Extrafacial Lentigo Maligna: A Report on 14 Cases and a Review of the Literature.

作者信息

Martínez-Leboráns L, Garcías-Ladaria J, Oliver-Martínez V, Alegre de Miquel V

机构信息

Servicio de Dermatología, Hospital General Universitario de Valencia, Valencia, España.

Servicio de Dermatología, Hospital Manacor, Manacor, Mallorca, España.

出版信息

Actas Dermosifiliogr. 2016 Oct;107(8):e57-63. doi: 10.1016/j.ad.2015.10.018. Epub 2016 May 11.

Abstract

Lentigo maligna is the most common form of in situ melanoma. It is most often found on the head and neck, and its clinical and dermoscopic features in this location have been extensively described in the literature. We present a series of 14 patients diagnosed with extrafacial lentigo maligna and lentigo maligna melanoma at Hospital General de Valencia and Hospital de Manacor in Spain, and describe the clinical, dermoscopic, and histologic features observed. Most of the melanomas were located on the upper limbs; the next most common locations were the trunk and the lower limbs. The dermoscopic patterns were consistent with facial lentigo maligna and superficial spreading melanoma. Extrafacial lentigo maligna is uncommon. It has similar clinical and histologic features to facial lentigo, but dermoscopy may show a mix of patterns typically seen in lentigo maligna and superficial spreading melanoma. This difference in dermoscopic features is essentially due to anatomical differences between skin on the face and on other parts of the body.

摘要

恶性雀斑样痣是原位黑色素瘤最常见的形式。它最常出现在头颈部,其在此部位的临床和皮肤镜特征在文献中已有广泛描述。我们报告了西班牙巴伦西亚综合医院和马纳科尔医院诊断为面部以外恶性雀斑样痣和恶性雀斑样痣黑色素瘤的14例患者系列,并描述观察到的临床、皮肤镜和组织学特征。大多数黑色素瘤位于上肢;其次最常见的部位是躯干和下肢。皮肤镜表现与面部恶性雀斑样痣和浅表扩散性黑色素瘤一致。面部以外的恶性雀斑样痣并不常见。它具有与面部恶性雀斑样痣相似的临床和组织学特征,但皮肤镜检查可能显示出通常在恶性雀斑样痣和浅表扩散性黑色素瘤中见到的多种表现混合。皮肤镜特征的这种差异主要是由于面部皮肤与身体其他部位皮肤的解剖学差异所致。

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