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1992年至2012年间英国青少年中毒情况的变化:一项基于人群的队列研究。

Changes in poisonings among adolescents in the UK between 1992 and 2012: a population based cohort study.

作者信息

Tyrrell Edward G, Orton Elizabeth, Tata Laila J

机构信息

Division of Primary Care, School of Medicine, University of Nottingham, Nottingham, UK.

Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, UK.

出版信息

Inj Prev. 2016 Dec;22(6):400-406. doi: 10.1136/injuryprev-2015-041901. Epub 2016 May 16.

Abstract

BACKGROUND

Poisonings are a common cause of morbidity and mortality among adolescents. Yet surveillance data indicating current incidence rates (IRs) and time trends are lacking, making policy development and service planning difficult. We utilised population based primary care data to estimate adolescent poisoning rates according to intent across the UK.

METHODS

A cohort study of 1 311 021 adolescents aged 10-17 years, between 1992 and 2012, was conducted using routine primary care data from The Health Improvement Network. IRs and adjusted IRRs with 95% CIs were calculated for all poisonings, intentional, unintentional, unknown intent and alcohol related poisonings, by age, sex, calendar time and socioeconomic deprivation.

RESULTS

Overall poisoning incidence increased by 27% from the period 1992-1996 to 2007-2012, with the largest increases in intentional poisonings among females aged 16-17 years (IR 391.4/100 000 person years (PY), CI 328.9 to 465.7 for age 17 years in 1992-1996; 767.0/100 000 PY, CI 719.5 to 817.7 in 2007-2012) and alcohol related poisonings in females aged 15-16 years (IR 65.7/100 000 PY, CI 43.3 to 99.8 rising to 130.0/100 000 PY, CI 110.0 to 150.0 for age 15 years). A strong socioeconomic gradient for all poisonings persisted over time, with higher rates among the more deprived (IRR 2.63, CI 2.41 to 2.88 for the most vs least deprived quintile in 2007-2012).

CONCLUSIONS

Adolescent poisonings, especially intentional poisonings, have increased substantially over time and remain associated with health inequalities. Social and psychological support for adolescents should be targeted at more deprived communities, and child and adolescent mental health and alcohol support service provision should be commissioned to reflect the changing need.

摘要

背景

中毒是青少年发病和死亡的常见原因。然而,目前缺乏表明当前发病率(IR)和时间趋势的监测数据,这使得政策制定和服务规划变得困难。我们利用基于人群的初级保健数据来估计全英国青少年按中毒意图划分的中毒率。

方法

利用来自健康改善网络的常规初级保健数据,对1992年至2012年间1311021名10 - 17岁的青少年进行了队列研究。计算了所有中毒类型(故意中毒、非故意中毒、意图不明中毒和酒精相关中毒)按年龄、性别、日历时间和社会经济剥夺程度分类的发病率(IR)以及调整后的发病率比值比(IRR)和95%置信区间(CI)。

结果

从1992 - 1996年到2007 - 2012年,总体中毒发病率上升了27%,其中16 - 17岁女性的故意中毒增加最多(发病率:1992 - 1996年17岁时为391.4/100000人年,CI为328.9至465.7;2007 - 2012年为767.0/100000人年,CI为719.5至817.7),15 - 16岁女性的酒精相关中毒也有所增加(发病率:15岁时为65.7/100000人年,CI为43.3至99.8,升至130.0/100000人年,CI为110.0至150.0)。随着时间的推移,所有中毒类型都存在明显的社会经济梯度,最贫困人群的中毒率更高(2007 - 2012年,最贫困五分位数与最不贫困五分位数的发病率比值比为2.63,CI为2.41至2.88)。

结论

随着时间推移青少年中毒尤其是故意中毒大幅增加,且仍与健康不平等相关。对青少年的社会和心理支持应针对更贫困社区,儿童和青少年心理健康及酒精支持服务的提供应根据需求变化进行调整。

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