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隐球菌性脑膜炎作为艾滋病毒感染儿童的并发症:来自撒哈拉以南非洲的病例系列

Cryptococcal Meningitis Presenting as a Complication in HIV-infected Children: A Case Series From Sub-Saharan Africa.

作者信息

Nyazika Tinashe K, Masanganise Faith, Hagen Ferry, Bwakura-Dangarembizi Mutsawashe F, Ticklay Ismail M H, Robertson Valerie J

机构信息

From the Departments of *Chemical Pathology and †Medical Microbiology, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe; ‡Parirenyatwa Group of Hospitals, Causeway, Harare, Zimbabwe; §Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands; and ¶Department of Paediatrics and Child Health, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.

出版信息

Pediatr Infect Dis J. 2016 Sep;35(9):979-80. doi: 10.1097/INF.0000000000001212.

Abstract

Cryptococcal meningitis is a leading infectious disease worldwide as a result of the high burden of HIV and AIDS, although its cumulative incidence is very low in children compared with that in adults. Very few studies involving the disease in children have been reported including sub-Saharan Africa, with the highest prevalence of HIV-infected children in the world. We summarize 5 cases of children diagnosed with cryptococcal meningitis at a tertiary hospital in Harare, Zimbabwe, between October 1, 2013, and September 30, 2014.

摘要

由于艾滋病毒和艾滋病的高负担,隐球菌性脑膜炎是全球主要的传染病,尽管与成人相比,其在儿童中的累积发病率非常低。包括撒哈拉以南非洲在内,涉及该疾病在儿童中的研究报道极少,而撒哈拉以南非洲是世界上艾滋病毒感染儿童患病率最高的地区。我们总结了2013年10月1日至2014年9月30日期间在津巴布韦哈拉雷一家三级医院确诊为隐球菌性脑膜炎的5例儿童病例。

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