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颅内半球间骨软骨脂肪瘤:一种极其罕见疾病的诊断与手术挑战

Intracranial interhemispheric osteochondrolipoma: Diagnostic and surgical challenges in an extremely rare entity.

作者信息

Rajeshwari Madhu, Suri Vaishali, Kaur Kavneet, Suri Ashish, Garg Ajay, Sharma Mehar Chand, Sarkar Chitra

机构信息

Departments of Pathology, All India Institute of Medical Sciences, New Delhi, India.

Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Neuropathology. 2016 Oct;36(5):470-474. doi: 10.1111/neup.12294. Epub 2016 May 16.

Abstract

Intracranial lipomas are rare developmental lesions, predominantly occurring in the interhemispheric location. Osteochondrolipoma is an extremely rare variant of lipoma with osseous and chondroid differentiation. We present a case of interhemispheric osteochondrolipoma, in a 2.5-years-old male child which was detected antenatally, in association with corpus callosum agenesis. The lesion progressively increased in size with resulting compression of surrounding structures, and was subjected to microsurgical decompression. To the best of our knowledge, this is the first case of intracranial interhemispheric osteochondrolipoma in the existing medical literature. Peculiarities of this case and the diagnostic and surgical challenges are discussed.

摘要

颅内脂肪瘤是罕见的发育性病变,主要发生于大脑半球间区域。骨软骨脂肪瘤是脂肪瘤的一种极其罕见的变异类型,具有骨和软骨样分化。我们报告一例2.5岁男童的大脑半球间骨软骨脂肪瘤病例,该病例在产前被检测出,伴有胼胝体发育不全。病变大小逐渐增加,导致周围结构受压,遂接受显微手术减压。据我们所知,这是现有医学文献中首例颅内大脑半球间骨软骨脂肪瘤病例。本文讨论了该病例的特点以及诊断和手术挑战。

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