（拟南芥）卷曲4的不断发展的故事。
The growing story of (ARABIDOPSIS) CRINKLY 4.
作者信息
Czyzewicz Nathan, Nikonorova Natalia, Meyer Matthew R, Sandal Priyanka, Shah Shweta, Vu Lam Dai, Gevaert Kris, Rao A Gururaj, De Smet Ive
机构信息
Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Loughborough, LE12 5RD, UK.
Department of Plant Systems Biology, VIB, B-9052 Ghent University, Belgium Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium.
出版信息
J Exp Bot. 2016 Aug;67(16):4835-47. doi: 10.1093/jxb/erw192. Epub 2016 May 21.
Receptor kinases play important roles in plant growth and development, but only few of them have been functionally characterized in depth. Over the past decade CRINKLY 4 (CR4)-related research has peaked as a result of a newly discovered role of ARABIDOPSIS CR4 (ACR4) in the root. Here, we comprehensively review the available (A)CR4 literature and describe its role in embryo, seed, shoot, and root development, but we also flag an unexpected role in plant defence. In addition, we discuss ACR4 domains and protein structure, describe known ACR4-interacting proteins and substrates, and elaborate on the transcriptional regulation of ACR4 Finally, we address the missing knowledge in our understanding of ACR4 signalling.
受体激酶在植物生长发育中发挥着重要作用，但其中只有少数已得到深入的功能表征。在过去十年中，由于拟南芥CRINKLY 4（ACR4）在根中的新发现作用，与CRINKLY 4（CR4）相关的研究达到了顶峰。在这里，我们全面回顾了现有的（A）CR4文献，并描述了它在胚胎、种子、地上部分和根发育中的作用，但我们也指出了它在植物防御中的一个意外作用。此外，我们讨论了ACR4结构域和蛋白质结构，描述了已知的与ACR4相互作用的蛋白质和底物，并详细阐述了ACR4的转录调控。最后，我们阐述了在理解ACR4信号传导方面缺失的知识。
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