Long Brit, Koyfman Alex
Department of Emergency Medicine, San Antonio Military Medical Center, Fort Sam Houston, Texas.
Department of Emergency Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas.
J Emerg Med. 2016 Jun;50(6):839-47. doi: 10.1016/j.jemermed.2015.10.020. Epub 2016 May 20.
Headache is a common chief complaint in emergency departments, accounting for 2% of visits, and subarachnoid hemorrhage (SAH) is a life-threating cause of headache. This deadly disease is most commonly due to aneurysmal rupture. Various approaches exist for diagnosis, with recent studies evaluating these approaches. A great deal of controversy exists about the optimal diagnosis strategy for SAH.
This article in the Best Clinical Practice Series seeks to educate emergency physicians on the recent literature in the diagnosis of SAH and provide an evidence-based approach.
Various diagnostic strategies exist, including use of noncontrast head computed tomography (CT) alone, CT/lumbar puncture (LP) in combination, CT/CT angiography, and magnetic resonance imaging/magnetic resonance angiography. The use of clinical decision rules has also been espoused, and several contemporary studies have evaluated cerebrospinal fluid results of red blood cell count and xanthochromia in the diagnosis of SAH. Recent literature supports that a negative head CT done within 6 h of headache onset places the patient at a < 1% risk for SAH. With the complex literature, a shared decision-making model should be followed with options, risks, and benefits discussed with the patient.
Literature support exists for all of the diagnostic strategies. The American College of Emergency Physicians Clinical Policy supports CT and LP for definitive diagnosis. Risk stratification and a shared decision-making model with the patient should be followed, and a negative head CT within 6 h of headache onset places patient at a risk of < 1% for having SAH.
头痛是急诊科常见的主要症状,占就诊人数的2%,蛛网膜下腔出血(SAH)是头痛的一种危及生命的病因。这种致命疾病最常见的原因是动脉瘤破裂。诊断方法有多种,近期研究对这些方法进行了评估。关于SAH的最佳诊断策略存在大量争议。
本篇最佳临床实践系列文章旨在让急诊医生了解SAH诊断的最新文献,并提供基于证据的方法。
存在多种诊断策略,包括单独使用非增强头部计算机断层扫描(CT)、CT/腰椎穿刺(LP)联合使用、CT/CT血管造影以及磁共振成像/磁共振血管造影。临床决策规则的应用也得到了支持,并且一些当代研究评估了脑脊液中红细胞计数和黄变在SAH诊断中的结果。近期文献支持在头痛发作后6小时内进行的头部CT检查结果为阴性时,患者发生SAH的风险<1%。鉴于文献复杂,应采用共同决策模型,与患者讨论各种选择、风险和益处。
所有诊断策略都有文献支持。美国急诊医师学会临床政策支持采用CT和LP进行明确诊断。应进行风险分层并与患者采用共同决策模型,头痛发作后6小时内头部CT检查结果为阴性时,患者发生SAH的风险<1%。