Schmalz O
Medizinische Klinik 1, Abteilung für Onkologie und Palliativmedizin, HELIOS Universitätsklinikum Wuppertal, Heusnerstraße 40, 42283, Wuppertal, Deutschland.
Urologe A. 2016 Jun;55(6):748-55. doi: 10.1007/s00120-016-0117-2.
Retroperitoneal tumors are rare malignancies. The retroperitoneum can host a wide spectrum of pathologies including primary or metastatic lesions.
Treatment of retroperitoneal tumors is often associated with several challenges because of their relative late presentation and anatomic location.
Because of various pathologies, a detailed case history, laboratory investigation and ultrasound should be performed. Radiologic examinations remain a major component in the diagnosis. In addition to computed tomography, magnetic resonance imaging and positron emission tomography are used. Although radiologic findings are often unspecific, there are often typical findings such as dissemination, margins, vascularization and tumor texture which contribute to the differential diagnosis even before making a definitive diagnosis. Due to the complexity of primary retroperitoneal tumors, which require different treatments depending on the final diagnosis, the treatment approach should be determined in a multidisciplinary tumor conference prior to histological confirmation and initiation of treatment.
To ensure the best potential curative treatment modality for retroperitoneal tumors, treatment is best performed in high-volume centers by a multidisciplinary team.
腹膜后肿瘤是罕见的恶性肿瘤。腹膜后可出现多种病变,包括原发性或转移性病变。
由于腹膜后肿瘤出现相对较晚且位置特殊,其治疗常面临诸多挑战。
鉴于病变的多样性,应详细询问病史、进行实验室检查及超声检查。放射学检查仍是诊断的主要组成部分。除计算机断层扫描外,还使用磁共振成像和正电子发射断层扫描。尽管放射学表现通常不具特异性,但常有一些典型表现,如扩散、边缘、血管形成及肿瘤质地等,即使在明确诊断之前也有助于鉴别诊断。由于原发性腹膜后肿瘤的复杂性,其治疗需根据最终诊断采用不同方法,因此治疗方案应在组织学确诊及开始治疗前,通过多学科肿瘤会议确定。
为确保腹膜后肿瘤获得最佳潜在治愈性治疗方式,最好由多学科团队在大型中心进行治疗。