Nguyen-Trong Phuong-Khanh J, Alaswad Khaldoon, Karmpaliotis Dimitri, Lombardi William, Grantham J Aaron, Lembo Nicholas, Kandzari David, Karatasakis Aris, Karacsonyi Judit, Danek Barbara A, Rangan Bavana V, Roesle Michele, Ayers Colby R, Thompson Craig A, Banerjee Subhash, Brilakis Emmanouil S
Dallas VA Medical Center (111A), 4500 South Lancaster Road, Dallas, TX 75216 USA.
J Invasive Cardiol. 2016 Jun;28(6):218-24.
The use of saphenous vein grafts (SVGs) for retrograde native-vessel chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study.
We retrospectively reviewed the medical records and coronary angiograms of retrograde CTO-PCI performed through an SVG at four United States institutions between 2012 and 2013.
During the study period, retrograde CTO-PCI was performed in 144 of 572 cases (25.2%) and retrograde CTO-PCI via SVG in 21 patients (14.6% of all retrograde cases). Mean age was 71 ± 7 years and 95.2% of the patients were men. The CTO target vessel was the right coronary (38%), circumflex (38%), and left anterior descending (24%) artery. Mean J-CTO score was 3.5 ± 1.0. The most common reentry technique was reverse controlled antegrade dissection and reentry. Technical and procedural success rates were 86% and 81%, respectively, with retrograde SVG-PCI attempts being successful in 67%. A major adverse cardiac event occurred in 2 patients (1 periprocedural myocardial infarction and 1 tamponade resulting in death). Median contrast volume, fluoroscopy time, and procedure time were 250 mL, 91.6 minutes, and 214 minutes, respectively. Two SVGs were coiled due to competitive flow after CTO recanalization.
Retrograde native-vessel CTO-PCI via SVG represents a small proportion of retrograde CTO-PCIs and was associated with high technical success rates, but may carry increased risk for complications.
大隐静脉移植物(SVG)用于逆行自身血管慢性完全闭塞(CTO)经皮冠状动脉介入治疗(PCI)的研究有限。
我们回顾性分析了2012年至2013年间在美国四家机构通过SVG进行逆行CTO-PCI的病历和冠状动脉造影。
在研究期间,572例患者中有144例(25.2%)进行了逆行CTO-PCI,其中21例(占所有逆行病例的14.6%)通过SVG进行逆行CTO-PCI。平均年龄为71±7岁,95.2%的患者为男性。CTO靶血管为右冠状动脉(38%)、回旋支(38%)和左前降支(24%)。平均J-CTO评分为3.5±1.0。最常见的再入技术是逆向可控前向夹层分离和再入。技术成功率和手术成功率分别为86%和81%,逆行SVG-PCI尝试成功率为67%。2例患者发生主要不良心脏事件(1例围手术期心肌梗死和1例心包填塞导致死亡)。造影剂用量、透视时间和手术时间的中位数分别为250 mL、91.6分钟和214分钟。2条SVG在CTO再通后因血流竞争而盘绕。
通过SVG进行逆行自身血管CTO-PCI占逆行CTO-PCI的比例较小,技术成功率高,但可能增加并发症风险。