Yu Hui-jie, Xu Xiao-qin, Xu Song-ao, Cao Wei-zhong
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2016 Mar;36(3):289-93.
To observe analgesic and sedative effect of acupuncture combined with medicine (ACM) on patients undergiong cardiac surgery.
A total of 50 patients with cardiac surgery from January 2012 to October 2014 were randomly assigned to the conventional analgesia group (group A) and the ACM analgesia group (group B), 25 in each group. Patients in group A were subjected to analgesia and sedation by injecting dexmedetomidine, while patients in group B were subjected to analgesia and sedation by electro-acupuncture [EA, Shenting (GV24); Yintang (EX-HN3)] combined with injection of dexmedetomidine. Morphine hydrochloride injection was performed when analgesia and sedation effect was ineffective in the two groups. The indicators of patients at different time points in the two groups were observed, such as static and dynamic VAS scores, SAS scores, mean arterial pressure (MAP), heart rate (HR), oxygen saturation (SpO2). The injection dosage of dexmedetomidine and morphine hydrochloride, analgesia satisfaction rate, sedation satisfaction rate, the incidences of adverse reactions during treatment such as bradycardia and low blood pressure, mechanical ventilation time, ICU time, and hospitalization expense were observed and recorded in the two groups.
There was no statistical difference in static and dynamic VAS scores, SAS score, MAP, HR and SpO2 between the two groups at different time points (P > 0.05). The injection dosage of dexmedetomidine and morphine hydrochloride was significantly reduced in group B than in group A (P < 0.05). The analgesia satisfaction rate of patients in group B was much higher than that in group A (P < 0.05). The incidence of bradycardia also obviously decreased more in group B than in group A (P < 0.05). There was no statistical difference in patients' sedation satisfaction rate, incidences of low blood pressure, delirium, vomiting; mechanical ventilation time, ICU time, or hospitalization expense between the two groups (P > 0.05).
The analgesia method of ACM could reduce the dosage of traditional analgesic drugs and the occurrence of partial adverse reactions.
观察针刺联合药物对心脏手术患者的镇痛镇静效果。
选取2012年1月至2014年10月行心脏手术的患者50例，随机分为传统镇痛组（A组）和针刺联合药物镇痛组（B组），每组25例。A组患者采用右美托咪定注射进行镇痛镇静，B组患者采用电针[神庭（GV24）、印堂（EX-HN3）]联合右美托咪定注射进行镇痛镇静。两组镇痛镇静效果不佳时均给予盐酸吗啡注射液。观察两组患者不同时间点的静息和动态视觉模拟评分（VAS）、焦虑自评量表（SAS）评分、平均动脉压（MAP）、心率（HR）、血氧饱和度（SpO2）等指标。记录两组右美托咪定和盐酸吗啡注射液的注射用量、镇痛满意率、镇静满意率、治疗期间心动过缓和低血压等不良反应的发生率、机械通气时间、重症监护病房（ICU）停留时间及住院费用。
两组不同时间点的静息和动态VAS评分、SAS评分、MAP、HR及SpO2比较，差异无统计学意义（P＞0.05）。B组右美托咪定和盐酸吗啡注射液的注射用量明显低于A组（P＜0.05）。B组患者的镇痛满意率明显高于A组（P＜0.05）。B组心动过缓的发生率也明显低于A组（P＜0.05）。两组患者的镇静满意率、低血压、谵妄、呕吐的发生率、机械通气时间、ICU停留时间及住院费用比较，差异无统计学意义（P＞0.05）。
针刺联合药物的镇痛方法可减少传统镇痛药物的用量及部分不良反应的发生。
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