追随北卡累利阿项目的脚步：2型糖尿病的预防

Following in the Footsteps of the North Karelia Project: Prevention of Type 2 Diabetes.

作者信息

Lindström Jaana, Uusitupa Matti, Tuomilehto Jaakko, Peltonen Markku

机构信息

Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.

Department of Clinical Nutrition, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland; Research Unit, Kuopio University Hospital, Kuopio, Finland.

出版信息

Glob Heart. 2016 Jun;11(2):223-8. doi: 10.1016/j.gheart.2016.04.003.

DOI:10.1016/j.gheart.2016.04.003

PMID:27242091

Abstract

The prevalence as well as actual number of people with type 2 diabetes has been increasing in Finland during the past decades, in parallel with an increase in overweight and obesity. Besides obesity, population aging is among the main drivers of increasing numbers of diabetic patients. Type 2 diabetes brings along complications, most importantly cardiovascular diseases, and increasing type 2 diabetes prevalence has also been suggested to lead to a new upward turn in cardiovascular diseases. Therefore, it is important to implement activities to prevent type 2 diabetes. We present the trial evidence for the prevention of type 2 diabetes with emphasis on the Finnish Diabetes Prevention Study findings. Furthermore, we discuss the practical implementation of screening of individuals for high type 2 diabetes risk and prevention of type 2 diabetes in Finland at the population level and describe how they have contributed to European level initiatives.

摘要

在过去几十年中，芬兰2型糖尿病患者的患病率及实际人数一直在增加，与此同时超重和肥胖现象也在增多。除肥胖外，人口老龄化也是糖尿病患者数量增加的主要驱动因素之一。2型糖尿病会引发并发症，其中最重要的是心血管疾病，而且2型糖尿病患病率的上升也被认为会导致心血管疾病出现新的上升趋势。因此，开展预防2型糖尿病的活动很重要。我们展示了预防2型糖尿病的试验证据，重点介绍了芬兰糖尿病预防研究的结果。此外，我们还讨论了在芬兰对2型糖尿病高风险个体进行筛查以及在人群层面预防2型糖尿病的实际实施情况，并描述了它们如何为欧洲层面的举措做出贡献。