Schneider Heiko, Uebing Anselm, Shore Darryl F
Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, UK -
J Cardiovasc Surg (Torino). 2016 Aug;57(4):557-68. Epub 2016 May 31.
Coarctation of the aorta (CoA), a juxtaductal obstructive lesion in the descending aorta and commonly associated with hypoplasia of the aortic arch occurs in 5-8% of patients with congenital heart disease. Since the initial surgical corrections in the 1950, surgical and transcatheter options have constantly evolved. Nowadays, transcatheter options are widely accepted as the initial treatment of choice in adults presenting with native or recurrent CoA. Surgical techniques are mainly reserved for patients with complex aortic arch anatomy such as extended arch hypoplasia or stenosis or para-CoA aneurysm formation. Extended aneurysms can be covered by conformable stents but stent implantation may require preparative vascular surgery. Complex re-CoA my best be treated by an ascending to descending bypass conduit. The following review aims to describe current endovascular and surgical practice pointing out modern developments and their limitations.
主动脉缩窄(CoA)是降主动脉的一种导管旁阻塞性病变,通常与主动脉弓发育不全相关,在5% - 8%的先天性心脏病患者中出现。自20世纪50年代首次进行手术矫正以来,手术和经导管治疗方法不断发展。如今,经导管治疗方法被广泛接受为成人原发性或复发性CoA的首选初始治疗方法。手术技术主要保留用于具有复杂主动脉弓解剖结构的患者,如广泛的弓发育不全或狭窄或缩窄旁动脉瘤形成。扩展的动脉瘤可用顺应性支架覆盖,但支架植入可能需要术前血管手术。复杂的复发性CoA最好通过升主动脉至降主动脉旁路管道治疗。以下综述旨在描述当前的血管内和手术实践,指出现代进展及其局限性。