气味剂复杂性对人体呼吸分形动力学的影响分析

The Analysis of the Influence of Odorant's Complexity on Fractal Dynamics of Human Respiration.

作者信息

Namazi Hamidreza, Akrami Amin, Kulish Vladimir V

机构信息

School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore.

School of Metallurgy and Material engineering, University of Tehran, Iran.

出版信息

Sci Rep. 2016 May 31;6:26948. doi: 10.1038/srep26948.

DOI:10.1038/srep26948

PMID:27244590

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4886627/

Abstract

One of the major challenges in olfaction research is to relate the structural features of the odorants to different features of olfactory system. However, no relationship has been yet discovered between the structure of the olfactory stimulus, and the structure of respiratory signal. This study reveals the plasticity of human respiratory signal in relation to 'complex' olfactory stimulus (odorant). We demonstrated that fractal temporal structure of respiration dynamics shifts towards the properties of the odorants used. The results show for the first time that more structurally complex a monomolecular odorant will result in less fractal respiratory signal. On the other hand, odorant with higher entropy will result the respiratory signal with lower entropy. The capability observed in this research can be further investigated and applied for treatment of patients with different respiratory diseases.

摘要

嗅觉研究中的一个主要挑战是将气味分子的结构特征与嗅觉系统的不同特征联系起来。然而，尚未发现嗅觉刺激的结构与呼吸信号的结构之间存在关联。本研究揭示了人类呼吸信号相对于“复杂”嗅觉刺激（气味分子）的可塑性。我们证明了呼吸动力学的分形时间结构向所使用气味分子的特性转变。结果首次表明，单分子气味分子的结构越复杂，呼吸信号的分形性就越低。另一方面，具有较高熵的气味分子将导致具有较低熵的呼吸信号。本研究中观察到的这种能力可以进一步研究并应用于治疗不同的呼吸系统疾病患者。