TMEM16F: function from (iso)form.

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作者信息

Acheson Kathryn

机构信息

Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.

出版信息

J Physiol. 2016 Jun 1;594(11):2785-6. doi: 10.1113/JP271980.

DOI:10.1113/JP271980

PMID:27246546

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4887666/

Abstract

摘要

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引用本文的文献

A major interspecies difference in the ionic selectivity of megakaryocyte Ca-activated channels sensitive to the TMEM16F inhibitor CaCCinh-A01.

Platelets. 2019;30(8):962-966. doi: 10.1080/09537104.2019.1595560. Epub 2019 Apr 22.

本文引用的文献

Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms.

J Physiol. 2015 Sep 1;593(17):3829-48. doi: 10.1113/JP270691. Epub 2015 Jul 27.

X-ray structure of a calcium-activated TMEM16 lipid scramblase.

Nature. 2014 Dec 11;516(7530):207-12. doi: 10.1038/nature13984. Epub 2014 Nov 12.

Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel.

Nat Commun. 2013;4:2367. doi: 10.1038/ncomms3367.

TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation.

Cell. 2012 Sep 28;151(1):111-22. doi: 10.1016/j.cell.2012.07.036.

Constitutive exposure of phosphatidylserine on viable cells.

Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19246-51. doi: 10.1073/pnas.1114799108. Epub 2011 Nov 14.

Calcium-dependent phospholipid scrambling by TMEM16F.

Nature. 2010 Dec 9;468(7325):834-8. doi: 10.1038/nature09583. Epub 2010 Nov 24.

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相似文献

TMEM16F: function from (iso)form.

J Physiol. 2016 Jun 1;594(11):2785-6. doi: 10.1113/JP271980.

TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets.

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12800-5. doi: 10.1073/pnas.1516594112. Epub 2015 Sep 28.

Phospholipid scrambling on the plasma membrane.

Methods Enzymol. 2014;544:381-93. doi: 10.1016/B978-0-12-417158-9.00015-7.

Single-molecule analysis of phospholipid scrambling by TMEM16F.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3066-3071. doi: 10.1073/pnas.1717956115. Epub 2018 Mar 5.

Role of Ca(2+) in the Stability and Function of TMEM16F and 16K.

Biochemistry. 2016 Jun 14;55(23):3180-8. doi: 10.1021/acs.biochem.6b00176. Epub 2016 Jun 3.

Regulation and Function of TMEM16F in Renal Podocytes.

Int J Mol Sci. 2018 Jun 18;19(6):1798. doi: 10.3390/ijms19061798.

TMEM16F-Mediated Platelet Membrane Phospholipid Scrambling Is Critical for Hemostasis and Thrombosis but not Thromboinflammation in Mice-Brief Report.

Arterioscler Thromb Vasc Biol. 2016 Nov;36(11):2152-2157. doi: 10.1161/ATVBAHA.116.307727. Epub 2016 Sep 15.

Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms.

J Physiol. 2015 Sep 1;593(17):3829-48. doi: 10.1113/JP270691. Epub 2015 Jul 27.

Phosphatidylinositol-(4, 5)-bisphosphate regulates calcium gating of small-conductance cation channel TMEM16F.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1667-E1674. doi: 10.1073/pnas.1718728115. Epub 2018 Jan 30.

TMEM16F Regulates Spinal Microglial Function in Neuropathic Pain States.

Cell Rep. 2016 Jun 21;15(12):2608-15. doi: 10.1016/j.celrep.2016.05.039.

引用本文的文献

A major interspecies difference in the ionic selectivity of megakaryocyte Ca-activated channels sensitive to the TMEM16F inhibitor CaCCinh-A01.

Platelets. 2019;30(8):962-966. doi: 10.1080/09537104.2019.1595560. Epub 2019 Apr 22.

本文引用的文献

Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms.

J Physiol. 2015 Sep 1;593(17):3829-48. doi: 10.1113/JP270691. Epub 2015 Jul 27.

X-ray structure of a calcium-activated TMEM16 lipid scramblase.

Nature. 2014 Dec 11;516(7530):207-12. doi: 10.1038/nature13984. Epub 2014 Nov 12.

Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel.

Nat Commun. 2013;4:2367. doi: 10.1038/ncomms3367.

TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation.

Cell. 2012 Sep 28;151(1):111-22. doi: 10.1016/j.cell.2012.07.036.

Constitutive exposure of phosphatidylserine on viable cells.

Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19246-51. doi: 10.1073/pnas.1114799108. Epub 2011 Nov 14.

Calcium-dependent phospholipid scrambling by TMEM16F.

Nature. 2010 Dec 9;468(7325):834-8. doi: 10.1038/nature09583. Epub 2010 Nov 24.