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腹内斜肌的低级别纤维黏液样肉瘤

A Low-Grade Fibromyxoid Sarcoma of the Internal Abdominal Oblique Muscle.

作者信息

Hashimoto Masakazu, Koide Kei, Arita Michinori, Kawaguchi Koji, Mikuriya Yoshihiro, Iwata Jun, Iwamoto Toshiyuki

机构信息

Department of Surgery, Chuden Hospital, 3-4-27 Otemachi, Naka-Ku, Hiroshima 730-8562, Japan.

Department of Diagnostic Pathology, Kochi Health Sciences Center, 2125-1 Ike, Kochi 781-8555, Japan.

出版信息

Case Rep Surg. 2016;2016:8524030. doi: 10.1155/2016/8524030. Epub 2016 May 10.

Abstract

A low-grade fibromyxoid sarcoma (LGFMS) is a rare tumor, with a benign histologic appearance but malignant behavior. This report describes a 74-year-old man with an internal abdominal oblique muscle mass. The tumor appeared as a well-defined ovoid mass on computed tomography, with mild uptake on fluorine-18-fluorodeoxyglucose positron-emission tomography images. Radical resection with wide safe margins was performed. Histologically, the tumor was composed of spindle-shaped cells in a whorled growth pattern, with alternating fibrous and myxoid stroma. MUC4 expression, a highly sensitive and specific immunohistochemical marker for LGFMS, was detected. Therefore, we diagnosed the tumor as LGFMS. At the 3-month follow-up, there was no sign of recurrence or metastasis. We report the first case of LGFMS arising from the internal abdominal oblique muscle.

摘要

低度纤维黏液样肉瘤(LGFMS)是一种罕见肿瘤,具有良性的组织学表现但行为恶性。本报告描述了一名74岁男性,其腹内斜肌有肿物。该肿瘤在计算机断层扫描上表现为边界清晰的椭圆形肿物,在氟-18-氟脱氧葡萄糖正电子发射断层扫描图像上有轻度摄取。进行了带广泛安全切缘的根治性切除。组织学上,肿瘤由呈漩涡状生长模式的梭形细胞组成,伴有交替的纤维性和黏液样间质。检测到MUC4表达,这是LGFMS一种高度敏感和特异的免疫组化标志物。因此,我们将该肿瘤诊断为LGFMS。在3个月的随访中,没有复发或转移的迹象。我们报告了首例起源于腹内斜肌的LGFMS病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feca/4877473/2c13f6bb8384/CRIS2016-8524030.001.jpg

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