Graham Jay A, Samstein Benjamin, Emond Jean C
Center for Liver Disease and Transplantation, Department of Surgery, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
Curr Transplant Rep. 2014 Mar;1(1):43-52. doi: 10.1007/s40472-013-0006-1.
LDLT has arisen as a viable means to reduce waitlist mortality. However, its widespread embrace by the liver transplant community has been met with frustration centered on donor morbidity and small-for-size-syndrome. Focusing on the later entity, we describe the initial recognition of this early graft dysfunction, the theorized pathophysiology and solutions to remedy its emergence.
活体肝移植已成为降低等待名单死亡率的一种可行方法。然而,肝移植界对其广泛接受却因供体并发症和小肝综合征而受挫。针对后一种情况,我们描述了对这种早期移植物功能障碍的最初认识、理论化的病理生理学以及解决其出现问题的方法。