Vaswani Ravi, Manoli Arthur, Goch Abraham, Egol Kenneth A
Bull Hosp Jt Dis (2013). 2016 Jun;74(2):160-4.
In end stage renal disease (ESRD) patients on hemodialysis (HD), it is known that renal bone disease has a negative impact on postoperative complication rate of fracture repair compared to non-ESRD patients. Previous studies have examined complications following surgical hip fracture repair in ESRD patients on HD. However, there is paucity of information outside of hip fracture repair. This study was undertaken to investigate complications associated with surgical fracture repair in ESRD patients on hemodialysis and to compare quality measures with a control group for various fracture types. Data of all consecutive ESRD patients on HD was collected prospectively starting in 2013. Charts of 2,558 ESRD patients on HD from 2010 to 2013 were also reviewed. Thirty-four patients who underwent surgical fracture repair were included in the study. Additionally, 1,000 patients without ESRD who underwent fracture repair were also identified, and a random sample of 267 patients was selected for inclusion as a control group. Primary outcomes were major complications as defined by the Clavien-Dindo complication rating system for orthopaedic surgery. Secondary outcomes were minor complications, defined by the same method. Demographic information and hospital quality measures, such as hospital length of stay (LOS) and discharge disposition, were also collected. There were no differences between the two groups in terms of BMI, ethnicity, or gender distribution. The ESRD patients were older than control patients (62.6 versus 46.8 years; p > 0.01). Overall, the complication rate in the ESRD group was 14.7% compared to 3% in the control group (p < 0.05) while the rate of major complications was similar (5.8% versus 2.2%, p = 0.2). The rate of minor complications was higher in the ESRD group though this did not reach statistical significance (8.8% versus 1%, p = 0.07). Median LOS was significantly higher in the ESRD group (15.9 versus 6.4 days; p < 0.01), and patients in the ESRD group were less likely to be discharged to home (29.4% versus 78%; p < 0.01). Surgical fracture repair in ESRD patients can be performed with similar major complication rate as a control group. However, the higher rate of minor complications and poorer hospital quality measures in the ESRD group must be taken into account as we move toward "pay for performance" and bundled payment initiatives for orthopaedic trauma patients.
在接受血液透析(HD)的终末期肾病(ESRD)患者中,已知与非ESRD患者相比,肾性骨病对骨折修复术后并发症发生率有负面影响。既往研究已探讨了接受HD的ESRD患者髋部骨折手术修复后的并发症情况。然而,除髋部骨折修复外,相关信息较少。本研究旨在调查接受血液透析的ESRD患者手术骨折修复相关并发症,并将各种骨折类型的质量指标与对照组进行比较。自2013年起前瞻性收集所有连续性接受HD的ESRD患者的数据。还回顾了2010年至2013年期间2558例接受HD的ESRD患者的病历。本研究纳入了34例接受手术骨折修复的患者。此外,还确定了1000例未患ESRD且接受骨折修复的患者,并随机抽取267例患者作为对照组纳入研究。主要结局为根据骨科手术的Clavien-Dindo并发症分级系统定义的主要并发症。次要结局为采用相同方法定义的次要并发症。还收集了人口统计学信息和医院质量指标,如住院时间(LOS)和出院处置情况。两组在BMI、种族或性别分布方面无差异。ESRD患者比对照组患者年龄更大(62.6岁对46.8岁;p>0.01)。总体而言,ESRD组的并发症发生率为14.7%,而对照组为3%(p<0.05),而主要并发症发生率相似(5.8%对2.2%,p=0.2)。ESRD组的次要并发症发生率更高,尽管未达到统计学意义(8.8%对1%,p=0.07)。ESRD组的中位住院时间显著更长(15.9天对6.4天;p<0.01),且ESRD组患者出院回家的可能性更小(29.4%对78%;p<0.01)。ESRD患者的手术骨折修复可在与对照组相似的主要并发症发生率下进行。然而,在我们朝着骨科创伤患者的“按绩效付费”和捆绑支付倡议迈进时,必须考虑ESRD组中较高的次要并发症发生率和较差的医院质量指标。