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甲状腺手术中意外甲状旁腺切除的发生率及预测因素分析。

Analysis of the incidence and factors predictive of inadvertent parathyroidectomy during thyroid surgery.

作者信息

Hone R W A, Tikka T, Kaleva A I, Hoey A, Alexander V, Balfour A, Nixon I J

机构信息

Ear, Nose and Throat Department,William Harvey Hospital,Ashford,UK.

Ear, Nose and Throat Department,Heart of England NHS Foundation Trust,Birmingham,UK.

出版信息

J Laryngol Otol. 2016 Jul;130(7):669-73. doi: 10.1017/S0022215116008136. Epub 2016 Jun 10.

Abstract

BACKGROUND

Inadvertent (or incidental) parathyroidectomy can occur during thyroidectomy. However, the factors associated with inadvertent parathyroidectomy remain unclear. This study aimed to report the rate of inadvertent parathyroidectomy during thyroidectomy and associated risk factors.

METHODS

Variables including fine needle aspiration cytology findings, age, sex, thyroid weight, concurrent neck dissection, extent of thyroidectomy, and the presence of cancer and parathyroid tissue within the specimen were recorded for 266 patients. The incidence of post-operative hypocalcaemia was also recorded. Univariate and multivariate analysis were performed to identify factors associated with inadvertent parathyroidectomy.

RESULTS

The inadvertent parathyroidectomy rate was 16 per cent. Univariate analysis revealed that cancer and concurrent neck dissection predicted inadvertent parathyroidectomy. On multivariate analysis, only concurrent neck dissection remained an independent predictor of inadvertent parathyroidectomy: it was associated with a fourfold increase in inadvertent parathyroidectomy.

CONCLUSION

The inadvertent parathyroidectomy rate was 16 per cent and concurrent neck dissection was identified as an independent predictor of inadvertent parathyroidectomy.

摘要

背景

甲状腺切除术中可能会发生意外(或偶然)甲状旁腺切除术。然而,与意外甲状旁腺切除术相关的因素仍不清楚。本研究旨在报告甲状腺切除术中意外甲状旁腺切除术的发生率及相关危险因素。

方法

记录了266例患者的变量,包括细针穿刺细胞学检查结果、年龄、性别、甲状腺重量、同期颈部淋巴结清扫、甲状腺切除范围以及标本中是否存在癌症和甲状旁腺组织。还记录了术后低钙血症的发生率。进行单因素和多因素分析以确定与意外甲状旁腺切除术相关的因素。

结果

意外甲状旁腺切除术的发生率为16%。单因素分析显示,癌症和同期颈部淋巴结清扫可预测意外甲状旁腺切除术。多因素分析显示,只有同期颈部淋巴结清扫仍然是意外甲状旁腺切除术的独立预测因素:它与意外甲状旁腺切除术增加四倍相关。

结论

意外甲状旁腺切除术的发生率为16%,同期颈部淋巴结清扫被确定为意外甲状旁腺切除术的独立预测因素。

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