Choi Namkee G, DiNitto Diana M, Marti C Nathan
University of Texas at Austin School of Social Work, 1925 San Jacinto Blvd, Austin, TX 78712, United States.
University of Texas at Austin School of Social Work, 1925 San Jacinto Blvd, Austin, TX 78712, United States.
Drug Alcohol Depend. 2016 Aug 1;165:94-102. doi: 10.1016/j.drugalcdep.2016.05.023. Epub 2016 May 31.
The increasing numbers of older-adult marijuana users call for better understanding of their mental and substance use disorders (MSUDs).
Data came from the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC-III; N=14,715 respondents aged 50 +). Multinomial logistic regression analysis was used to compare never users, past-year users, and ex-users on past-year and lifetime MSUDs. Binary logistic regression analysis was used to examine the association of marijuana use patterns in the past year and during the peak use period with lifetime MSUDs.
Of the 50+ age group, 3.9% were past-year marijuana users and 21.7% were ex-users. Past-year users did not differ from ex-users with respect to past-year or lifetime mental disorders, but they had higher risks of past-year other drug use (RRR=2.73, 95% CI=1.63-4.55), alcohol use (RRR=2.30, 95% CI=1.78-2.98), and tobacco/nicotine use (RRR=1.87, 95% CI=1.50-2.34) disorders. Among past-year users, the number of joints smoked during the peak use period (OR=1.14, 95% CI=1.04-1.26) and past-year use frequency (OR=2.20, 95% CI=1.37-3.52) were significantly associated with greater odds of lifetime marijuana/other drug use disorder. Among ex-users, the number of joints smoked during the peak use period was significantly associated with any mental (OR=1.05, 95% CI=1.01-1.09) and marijuana and/or other drug use (OR=1.13, 95% CI=1.06-1.21) disorder.
Older-adult past-year marijuana users and ex-users had similarly high risks for past-year and lifetime mental disorders, but past-year users had a higher risk for substance use disorders. Health/mental health providers should be concerned about the increasing number of older-adult long-term marijuana users with MSUDs.
老年大麻使用者数量不断增加,这就需要更好地了解他们的精神和物质使用障碍(MSUDs)。
数据来自2012 - 2013年全国酒精及相关状况流行病学调查(NESARC - III;N = 14715名年龄在50岁及以上的受访者)。采用多项逻辑回归分析,比较从未使用者、过去一年使用者和既往使用者在过去一年及终生MSUDs方面的情况。采用二元逻辑回归分析,研究过去一年及使用高峰期的大麻使用模式与终生MSUDs之间的关联。
在50岁及以上年龄组中,3.9%为过去一年大麻使用者,21.7%为既往使用者。过去一年使用者在过去一年或终生精神障碍方面与既往使用者没有差异,但他们在过去一年其他药物使用障碍(相对风险比RRR = 2.73,95%置信区间CI = 1.63 - 4.55)、酒精使用障碍(RRR = 2.30,95% CI = 1.78 - 2.98)以及烟草/尼古丁使用障碍(RRR = 1.87,95% CI = 1.50 - 2.34)方面的风险更高。在过去一年使用者中,使用高峰期吸食的大麻烟卷数量(比值比OR = 1.14,95% CI = 1.04 - 1.26)和过去一年使用频率(OR = 2.20,95% CI = 1.37 - 3.52)与终生大麻/其他药物使用障碍的几率显著相关。在既往使用者中,使用高峰期吸食的大麻烟卷数量与任何精神障碍(OR = 1.05,95% CI = 1.01 - 1.09)以及大麻和/或其他药物使用障碍(OR = 1.13,95% CI = 1.06 - 1.21)显著相关。
老年过去一年大麻使用者和既往使用者在过去一年及终生精神障碍方面具有相似的高风险,但过去一年使用者在物质使用障碍方面风险更高。健康/心理健康提供者应关注患有MSUDs的老年长期大麻使用者数量的增加。