住院肿瘤患者艰难梭菌感染的流行病学
Epidemiology of Clostridium difficile infection in hospitalized oncology patients.
作者信息
Chang Gina Y, Dembry Louise M, Banach David B
机构信息
Yale School of Public Health, New Haven, CT; Albert Einstein College of Medicine, Bronx, NY.
Yale School of Public Health, New Haven, CT; Yale School of Medicine, New Haven, CT.
出版信息
Am J Infect Control. 2016 Nov 1;44(11):1408-1410. doi: 10.1016/j.ajic.2016.04.210. Epub 2016 Jun 7.
The epidemiology of Clostridium difficile infection (CDI) among oncology inpatients is poorly understood. In multivariate analysis we identified age, history of CDI, and prior receipt of cephalosporins, β-lactam/β-lactamase inhibitors, metronidazole, and blood transfusion as risk factors associated with CDI. Reducing broad-spectrum antibiotic use, particularly among older patients and those with a CDI history and recent blood transfusions, may decrease CDI risk in this population.
艰难梭菌感染（CDI）在肿瘤住院患者中的流行病学情况尚不清楚。在多变量分析中，我们确定年龄、CDI病史以及先前使用头孢菌素、β-内酰胺/β-内酰胺酶抑制剂、甲硝唑和输血为与CDI相关的危险因素。减少广谱抗生素的使用，尤其是在老年患者、有CDI病史的患者以及近期接受输血的患者中减少使用，可能会降低该人群发生CDI的风险。
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