Dept of Pathophysiology and Transplantation, University of Milan, Cardio-thoracic unit and Adult Cystic Fibrosis Center, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy
European Lung Foundation, Sheffield, UK.
Eur Respir J. 2016 Sep;48(3):632-47. doi: 10.1183/13993003.01888-2015. Epub 2016 Jun 10.
Bronchiectasis is a disease of renewed interest in light of an increase in prevalence and increasing burden on international healthcare systems. There are no licensed therapies, and large gaps in knowledge in terms of epidemiology, pathophysiology and therapy. The European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) is a European Respiratory Society (ERS) Clinical Research Collaboration, funded by ERS to promote high-quality research in bronchiectasis. The objective of this consensus statement was to define research priorities in bronchiectasis. From 2014 to 2015, EMBARC used a modified Delphi process among European bronchiectasis experts to reach a consensus on 55 key research priorities in this field. During the same period, the European Lung Foundation collected 711 questionnaires from adult patients with bronchiectasis and their carers from 22 European countries reporting important research priorities from their perspective. This consensus statement reports recommendations for bronchiectasis research after integrating both physicians and patients priorities, as well as those uniquely identified by the two groups. Priorities identified in this consensus statement provide the clearest possible roadmap towards improving our understanding of the disease and the quality of care for patients with bronchiectasis.
支气管扩张症的发病率不断上升,对国际医疗体系的负担也日益加重,这一疾病再次引起了人们的关注。目前尚无获批的治疗方法,在流行病学、病理生理学和治疗方面仍存在大量知识空白。欧洲支气管扩张症多中心审核和研究协作组(EMBARC)是一个由欧洲呼吸学会(ERS)资助的临床研究协作组,旨在促进支气管扩张症领域的高质量研究。本共识声明旨在确定支气管扩张症的研究重点。2014 年至 2015 年期间,EMBARC 在欧洲支气管扩张症专家中使用改良 Delphi 法,就该领域的 55 项关键研究重点达成共识。同期,欧洲肺基金会(European Lung Foundation)从 22 个欧洲国家的 711 名支气管扩张症成年患者及其护理人员那里收集了问卷,报告了从他们的角度来看重要的研究重点。本共识声明在综合医生和患者的重点以及这两个群体特有的重点的基础上,提出了支气管扩张症研究的建议。本共识声明中确定的重点为我们进一步了解该疾病和提高支气管扩张症患者的护理质量提供了最清晰的路线图。