颈部和迟发性肌张力障碍中苍白球的局部场电位振荡
Local field potential oscillations of the globus pallidus in cervical and tardive dystonia.
作者信息
Trenado Carlos, Hartmann Christian J, Elben Saskia, Pauls K Amande M, Friggemann Lena, Groiss Stefan Jun, Timmermann Lars, Vesper Jan, Schnitzler Alfons, Wojtecki Lars
机构信息
Heinrich Heine University, Medical Faculty, Institute of Clinical Neuroscience and Medical Psychology, Duesseldorf, Germany; Heinrich Heine University, Medical Faculty, Department of Neurology, Center for Movement Disorders and Neuromodulation, Duesseldorf, Germany.
Heinrich Heine University, Medical Faculty, Institute of Clinical Neuroscience and Medical Psychology, Duesseldorf, Germany.
出版信息
J Neurol Sci. 2016 Jul 15;366:68-73. doi: 10.1016/j.jns.2016.04.033. Epub 2016 Apr 19.
BACKGROUND
Reports about neural oscillatory activity in the globus pallidus internus (GPi) have targeted general (GD) and cervical dystonia (CD), however to our knowledge they are nonexistent for tardive dystonia (TD).
METHODS
Local field potentials (LFPs) from seven CD and five TD patients were recorded intraoperatively. We compared LFP power in thetadelta, alpha and beta band during rest and sensory palmar stimulation (SPS) in patients with general anesthesia and local/analgo sedation.
RESULTS
We found prominent LFP power activity in thetadelta for both CD and TD. Unlike TD, a significant difference between rest and SPS was revealed for CD.
CONCLUSIONS
Our data support the presence of LFP oscillatory activity in CD and TD. Thetadelta power modulation in the GPi is suggested as a signature for sensory processing in CD.
背景
关于内侧苍白球（GPi）神经振荡活动的报道主要针对全身性肌张力障碍（GD）和颈部肌张力障碍（CD），然而据我们所知，迟发性肌张力障碍（TD）尚无此类报道。
方法
术中记录了7例CD患者和5例TD患者的局部场电位（LFP）。我们比较了全身麻醉和局部/镇痛镇静患者在静息状态和感觉性掌部刺激（SPS）期间，θ/δ、α和β频段的LFP功率。
结果
我们发现CD和TD患者在θ/δ频段均有显著的LFP功率活动。与TD不同，CD患者在静息和SPS之间存在显著差异。
结论
我们的数据支持CD和TD中存在LFP振荡活动。GPi中θ/δ功率调制被认为是CD感觉处理的特征。
Zotero 插件