Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, People's Republic of China; email:
State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing 100871, People's Republic of China; email:
Annu Rev Phytopathol. 2016 Aug 4;54:99-120. doi: 10.1146/annurev-phyto-080615-095900. Epub 2016 May 25.
Rice reoviruses, transmitted by leafhopper or planthopper vectors in a persistent propagative manner, seriously threaten the stability of rice production in Asia. Understanding the mechanisms that enable viral transmission by insect vectors is a key to controlling these viral diseases. This review describes current understanding of replication cycles of rice reoviruses in vector cell lines, transmission barriers, and molecular determinants of vector competence and persistent infection. Despite recent breakthroughs, such as the discoveries of actin-based tubule motility exploited by viruses to overcome transmission barriers and mutually beneficial relationships between viruses and bacterial symbionts, there are still many gaps in our knowledge of transmission mechanisms. Advances in genome sequencing, reverse genetics systems, and molecular technologies will help to address these problems. Investigating the multiple interaction systems among the virus, insect vector, insect symbiont, and plant during natural infection in the field is a central topic for future research on rice reoviruses.
水稻呼肠孤病毒通过叶蝉或飞虱以持久增殖的方式传播，严重威胁亚洲水稻生产的稳定性。了解昆虫媒介传播病毒的机制是控制这些病毒病的关键。本综述描述了水稻呼肠孤病毒在媒介细胞系中的复制周期、传播障碍以及媒介适合性和持续感染的分子决定因素的最新理解。尽管最近取得了一些突破，例如发现了病毒利用肌动蛋白为基础的小管运动来克服传播障碍以及病毒和细菌共生体之间互惠互利的关系，但我们对传播机制的认识仍然存在许多空白。基因组测序、反向遗传学系统和分子技术的进步将有助于解决这些问题。在田间自然感染过程中研究病毒、昆虫媒介、昆虫共生体和植物之间的多个相互作用系统是未来研究水稻呼肠孤病毒的一个核心课题。
