Alasheev A M, Andreev A Yu, Gonysheva Yu V, Lagutenko M N, Lipin G I, Lokteva E E, Luckovich O Yu, Mamonova A V, Prazdnichkova E V, Belkin A A
Sverdlovsk Regional Clinical Hospital #1, Ekaterinberg.
Zh Nevrol Psikhiatr Im S S Korsakova. 2016;116(3 Pt 2):23-27. doi: 10.17116/jnevro20161163223-27.
Telestroke videoconference for conducting the National Institute of Health Stroke Scale (NIHSS) is recommended when direct bedside evaluation by a stroke specialist is not immediately available for hyperacute stroke assessment. However, some NIHSS-telestroke studies inherit systematic bias due to subjectivity of NIHSS administration. Authors aimed to evaluate NIHSS telestroke assessment, while implementing measures to minimize subjectivity bias.
Ninety acute stroke patients within 48 hours of onset were assessed by 6 stroke neurologists grouped in 15 pairs. Each pair of physicians assessed 6 patients. Patients were allocated through block randomization to a physician pair and order of bedside or remote assessment. Every patient was assessed once at the bedside and once remotely. Remote examination was performed by a neurologist through high-quality videoconferencing, assisted by a nurse at the patient's bedside. Kappa coefficients and the number of patients with a cumulative difference of ≤3 NIHSS points were calculated to compare bedside and remote measures.
Cumulative difference of ≤3 NIHSS points was observed in 85.6% (95% CI 76.6%; 92.1%) cases. Therefore, every fifth remote examination may have been inaccurate. Quadratically weighted κ for total NIHSS score was 0.91 (95% CI 0.87; 0.95). Minimal agreements were for commands (κ=0.46), facial palsy (κ=0.43), and ataxia (κ=0.27). Remote assessments were longer than bedside: 8 minutes (IQR 7; 9) versus 6 (IQR 5; 8), p<0.001.
NIHSS-telestroke assessment using high-quality videoconferencing in the acute stroke settings is closely matched with NIHSS-bedside assessment but it's credibility for clinical use needs further evaluation.
当无法立即由卒中专家进行直接床边评估以对超急性卒中进行评估时,推荐使用远程卒中视频会议来进行美国国立卫生研究院卒中量表(NIHSS)评估。然而,由于NIHSS评估的主观性,一些NIHSS远程卒中研究存在系统偏差。作者旨在评估NIHSS远程卒中评估,同时采取措施尽量减少主观偏差。
90例发病48小时内的急性卒中患者由6名卒中神经科医生分成15对进行评估。每对医生评估6例患者。患者通过区组随机化分配给一对医生以及床边或远程评估的顺序。每位患者在床边和远程各评估一次。远程检查由一名神经科医生通过高质量视频会议进行,患者床边有一名护士协助。计算kappa系数以及累积差异≤3分的患者数量,以比较床边和远程测量结果。
85.6%(95%可信区间76.6%;92.1%)的病例观察到累积差异≤3分。因此,每五次远程检查可能有一次不准确。NIHSS总分的二次加权κ值为0.91(95%可信区间0.87;0.95)。一致性最低的是指令(κ=0.46)、面瘫(κ=0.43)和共济失调(κ=0.27)。远程评估比床边评估时间长:8分钟(四分位间距7;9)对6分钟(四分位间距5;8),p<0.001。
在急性卒中环境中使用高质量视频会议进行NIHSS远程卒中评估与NIHSS床边评估密切匹配,但其临床应用的可信度需要进一步评估。