Department Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-0033, Japan.
Curr Opin Plant Biol. 2016 Oct;33:42-47. doi: 10.1016/j.pbi.2016.06.003. Epub 2016 Jun 14.
The vascular system spreads throughout the plant body. This highly organized network contains several types of cells. Vascular cell development is initiated during embryogenesis, and then vascular cells proliferate, form a vascular pattern, and commit to specific cell fates. Recent molecular genetics and modeling approaches have increased our understanding of the molecular mechanisms underlying early vascular development. Early events during vascular development are tightly linked and controlled by transcriptional complexes consisting of LONESOME HIGHWAY (LHW) and TARGET OF MONOPTEROS5 (TMO5) families. The role of LHW-TMO5 is tightly coupled with biosynthesis and/or signaling of phytohormones such as auxin and cytokinin. In this review, we discuss the regulatory network mediated by LHW-TMO5 during early vascular development.
植物的维管系统遍布全身。这个高度组织化的网络包含多种类型的细胞。维管细胞的发育始于胚胎发生，然后维管细胞增殖，形成维管模式，并决定特定的细胞命运。最近的分子遗传学和建模方法提高了我们对早期血管发育分子机制的理解。血管发育早期的事件紧密相连，并受到由 LONESOME HIGHWAY (LHW) 和 TARGET OF MONOPTEROS5 (TMO5) 家族组成的转录复合物的控制。LHW-TMO5 的作用与植物激素（如生长素和细胞分裂素）的生物合成和/或信号转导紧密相关。在这篇综述中，我们讨论了 LHW-TMO5 在早期血管发育过程中介导的调控网络。
