Visudhiphan P, Chiemchanya S, Dheandhanoo D
J Med Assoc Thai. 1989 Jan;72 Suppl 1:102-8.
Brain tumors remain the second most common neoplasm of childhood, however, there is no adequate study of this disease in Thai children. From the year 1971 to 1987, 468 children under 15 years of age were admitted to the Department of Pediatrics, Ramathibodi hospital with the diagnosis of brain tumor. Four hundred and forty-four patients had primary intracranial tumors, of these, 17 were excluded due to inadequate information and the remaining 427 patients were studied. Male to female ratio was 1.3:1, the age ranged from one day old to 14 years old. The duration of illness before admission ranged from a few days to 4 years, with over 70 per cent within 3 months. Headache, vomiting and papilledema were the three most common symptoms and signs. Supratentorial and infratentoral tumors were seen in 209 and 216 patients respectively, craniopharyngioma was the most common supratentorial tumor (51/209) and medulloblastoma was the most common infratentorial tumor (95/216), however, malignant astrocytoma is the overall most common tumor type. Early diagnosis and treatment were needed for good outcome.
脑肿瘤仍是儿童期第二常见的肿瘤,然而,泰国儿童中对这种疾病尚无充分的研究。1971年至1987年期间,468名15岁以下儿童因脑肿瘤诊断入住拉玛蒂博迪医院儿科。444例患者患有原发性颅内肿瘤,其中17例因信息不足被排除,其余427例患者接受研究。男女比例为1.3:1,年龄范围从1日龄至14岁。入院前病程从几天到4年不等,超过70%在3个月内。头痛、呕吐和视乳头水肿是最常见的三种症状和体征。幕上和幕下肿瘤分别见于209例和216例患者,颅咽管瘤是最常见的幕上肿瘤(51/209),髓母细胞瘤是最常见的幕下肿瘤(95/216),然而,恶性星形细胞瘤是总体上最常见的肿瘤类型。为获得良好预后需要早期诊断和治疗。