De Tobel Jannick, Hillewig Elke, Bogaert Stephanie, Deblaere Karel, Verstraete Koenraad
a Department of Radiology and Nuclear Medicine , Ghent University , Gent , Belgium.
b Ghent Institute for Functional and Metabolic Imaging (GIFMI) , Gent , Belgium.
Ann Hum Biol. 2017 Mar;44(2):130-139. doi: 10.1080/03014460.2016.1202321. Epub 2016 Jul 14.
Established dental age estimation methods in sub-adults study the development of third molar root apices on radiographs. In living individuals, however, avoiding ionising radiation is expedient. Studying dental development with magnetic resonance imaging complies with this requirement, adding the advantage of imaging in three dimensions.
To elaborate the development of an MRI protocol to visualise all third molars for forensic age estimation, with particular attention to the development of the root apex.
Ex vivo scans of porcine jaws and in vivo scans of 10 volunteers aged 17-25 years were performed to select adequate sequences. Studied parameters were T1 vs T2 weighting, ultrashort echo time (UTE), fat suppression, in plane resolution, slice thickness, 3D imaging, signal-to-noise ratio, and acquisition time. A bilateral four-channel flexible surface coil was used. Two observers evaluated the suitability of the images.
T2-weighted images were preferred to T1-weighted images. To clearly distinguish root apices in (almost) fully developed third molars an in plane resolution of 0.33 × 0.33 mm was deemed necessary. Taking acquisition time limits into account, only a T2 FSE sequence with slice thickness of 2 mm generated images with sufficient resolution and contrast. UTE, thinner slice T2 FSE and T2 3D FSE sequences could not generate the desired resolution within 6.5 minutes.
Three Tesla MRI of the third molars is a feasible technique for forensic age estimation, in which a T2 FSE sequence can provide the desired in plane resolution within a clinically acceptable acquisition time.
在亚成年人中,已有的牙龄估计方法是通过X光片研究第三磨牙根尖的发育情况。然而,对于活体个体而言,避免电离辐射更为便利。利用磁共振成像研究牙齿发育符合这一要求,且具有三维成像的优势。
精心制定一种磁共振成像方案,以显示所有第三磨牙用于法医年龄估计,尤其关注根尖的发育情况。
对猪颌骨进行离体扫描,并对10名年龄在17至25岁的志愿者进行活体扫描,以选择合适的序列。研究的参数包括T1加权与T2加权、超短回波时间(UTE)、脂肪抑制、平面分辨率、层厚、三维成像、信噪比和采集时间。使用双侧四通道柔性表面线圈。两名观察者评估图像的适用性。
T2加权图像优于T1加权图像。为了在(几乎)完全发育的第三磨牙中清晰区分根尖,认为平面分辨率为0.33×0.33毫米是必要的。考虑到采集时间限制,只有层厚为2毫米的T2 FSE序列能生成具有足够分辨率和对比度的图像。UTE、更薄层厚的T2 FSE和T2三维FSE序列在6.5分钟内无法生成所需分辨率。
对第三磨牙进行3特斯拉磁共振成像是一种可行的法医年龄估计技术,其中T2 FSE序列可在临床可接受的采集时间内提供所需的平面分辨率。