Suleiman Suleiman Hussein, Wadaella El Sammani, Fahal Ahmed Hassan
Mycetoma Research Centre, University of Khartoum, Khartoum, Sudan.
PLoS Negl Trop Dis. 2016 Jun 23;10(6):e0004690. doi: 10.1371/journal.pntd.0004690. eCollection 2016 Jun.
Surgical intervention is an integral component in the diagnosis and management of mycetoma. Surgical treatment is indicated for small, localised lesions and massive lesions to reduce the mycetoma load and to enable better response to medical therapy. It is also a life-saving procedure in patients with massive disease and sepsis. Surgical options for mycetoma treatment range from a wide local surgical excision to repetitive debridement excisions to amputation of the affected part. Adequate anaesthesia, a bloodless field, wide local excision with adequate safety margins in a suitable surgical facility, and expert surgeons are mandatory to achieve the best surgical outcome. Surgical intervention in mycetoma is associated with considerable morbidity, deformities, and disabilities, particularly in advanced disease. These complications can be reduced by educating patients to seek medical advice earlier when the lesion is small, localised, and amenable to surgery. There is no evidence for mycetoma hospital cross infection. This communication is based on the authors' experience in managing over 7,200 mycetoma patients treated at the Mycetoma Research Centre, University of Khartoum, Sudan.
手术干预是足菌肿诊断和治疗的一个重要组成部分。对于小的局限性病灶和巨大病灶,建议进行手术治疗,以减少足菌肿负荷,并使患者对药物治疗产生更好的反应。对于患有巨大疾病和败血症的患者,手术也是一种挽救生命的方法。足菌肿的手术治疗选择范围从广泛的局部手术切除到反复的清创切除,再到受影响部位的截肢。为了获得最佳手术效果,必须要有充分的麻醉、无血手术视野、在合适的手术设施中进行具有足够安全切缘的广泛局部切除,以及专业的外科医生。足菌肿的手术干预会带来相当大的发病率、畸形和残疾,尤其是在疾病晚期。通过教育患者在病灶小、局限且适合手术时尽早寻求医疗建议,可以减少这些并发症。没有证据表明足菌肿会在医院发生交叉感染。本交流基于作者在苏丹喀土穆大学足菌肿研究中心管理7200多名足菌肿患者的经验。