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年龄越大,跌倒越严重:地面跌倒后按年龄划分的损伤模式及后果

The older they are the harder they fall: Injury patterns and outcomes by age after ground level falls.

作者信息

Bhattacharya Bishwajit, Maung Adrian, Schuster Kevin, Davis Kimberly A

机构信息

Yale School of Medicine, Section of General Surgery, Trauma and Surgical Critical Care, Department of Surgery, New Haven, CT 06510, United States.

出版信息

Injury. 2016 Sep;47(9):1955-9. doi: 10.1016/j.injury.2016.06.019. Epub 2016 Jun 15.

Abstract

BACKGROUND

Trauma centers are seeing an increasing number of geriatric patients that are more susceptible to injuries even from relatively minor insults such as a ground level fall (GLF). As life expectancy increases, people are living in the geriatric age bracket for decades and often use anticoagulation agents for various comorbidities. We hypothesize that this patient population is not homogenous and we investigated the injury patterns and outcomes after GLF as a function of age and anticoagulation use. We also sought to identify injury patterns and patient characteristics of GLF patients.

METHODS

A retrospective review of a Level I trauma center's database identified all adult (age>18) trauma patients admitted after GLFs between 1/2003 and 12/2013. Demographics, injury patterns, antiplatelet use, anticoagulation use (including warfarin, enoxaparin, and rivaroxaban) and outcomes were abstracted.

RESULTS

The cohort included 5088 patients. 3990 patients were >60years and 38.2% were male. With each decade, although the mean ISS did not considerably change (range 7.0-8.6), mortality increased (0.9% at <60years vs. 5.5% at >90years), and the likelihood of home discharge decreased dramatically (73.7% at <60years vs. 18.2% at >90years). Abdominal solid organ injuries were rare (0.8%). Age was associated with an increased incidence of cervical spine (p=0.002), rib (p=0.009) and pelvic fractures (p<0.001). Only aspirin use was significantly associated with intracranial bleed (p=0.001). Aspirin (p=0.049) or warfarin (p<0.001) use was associated with increased overall mortality.

CONCLUSION

GLF patients are not homogenous as certain injury patterns change with increasing age. Aspirin use was associated with an increased incidence of intracranial bleeds, whereas other antiplatelet or anticoagulation agents were not. GLF is also associated with significant morbidity and mortality that increases dramatically with age. Both aspirin and warfarin are independently associated with increased mortality. These patient differences have implications for their evaluation and management.

LEVEL OF EVIDENCE

Epidemiological/prognostic study level IV.

摘要

背景

创伤中心接收的老年患者数量日益增多,这类患者即使受到相对轻微的损伤,如平地跌倒(GLF),也更容易受伤。随着预期寿命的增加,人们在老年阶段生活数十年,并且常常因各种合并症而使用抗凝剂。我们推测该患者群体并非同质化,因此我们研究了平地跌倒后的损伤模式和结局与年龄及抗凝剂使用之间的关系。我们还试图确定平地跌倒患者的损伤模式和患者特征。

方法

对一级创伤中心数据库进行回顾性分析,确定了2003年1月至2013年12月期间因平地跌倒入院的所有成年(年龄>18岁)创伤患者。提取了人口统计学数据、损伤模式、抗血小板药物使用情况、抗凝剂使用情况(包括华法林、依诺肝素和利伐沙班)及结局。

结果

该队列包括5088例患者。3990例患者年龄>60岁,男性占38.2%。每增长一个十年,尽管平均损伤严重度评分(ISS)没有显著变化(范围为7.0 - 8.6),但死亡率增加(<60岁时为0.9%,>90岁时为5.5%),回家出院的可能性显著降低(<60岁时为73.7%,>90岁时为18.2%)。腹部实性器官损伤很少见(0.8%)。年龄与颈椎骨折(p = 0.002)、肋骨骨折(p = 0.009)和骨盆骨折(p < 0.001)的发生率增加相关。仅阿司匹林的使用与颅内出血显著相关(p = 0.001)。阿司匹林(p = 0.049)或华法林(p < 0.001)的使用与总体死亡率增加相关。

结论

由于某些损伤模式随年龄增长而变化,平地跌倒患者并非同质化。阿司匹林的使用与颅内出血发生率增加相关,而其他抗血小板或抗凝剂则不然。平地跌倒还与显著的发病率和死亡率相关,且随着年龄增长而急剧增加。阿司匹林和华法林均独立与死亡率增加相关。这些患者差异对其评估和管理具有重要意义。

证据水平

流行病学/预后研究IV级。

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