PET/CT检查中上颌骨额突偶然发现的局灶性F-FDG摄取：患病率及临床意义

Incidental focal F-FDG uptake in the frontal process of the maxilla on PET/CT: prevalence and clinical significance.

作者信息

Park Soo Bin, Choi Joon Young, Kim Hyung-Jin, Kim Hye Jeong, Lee Kyung-Han, Kim Byung-Tae

机构信息

Department of Radiology, Soonchunhyang University Hospital, 59 Daesagwan-ro, Yongsan-gu, Seoul, 04401, Republic of Korea.

Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.

出版信息

Ann Nucl Med. 2016 Nov;30(9):619-623. doi: 10.1007/s12149-016-1103-x. Epub 2016 Jun 27.

DOI:10.1007/s12149-016-1103-x

PMID:27349660

Abstract

OBJECTIVE

We investigated the prevalence and clinical significance of incidental focal F-FDG uptake in the frontal process of the maxilla, mimicking malignancy on PET/CT.

METHODS

From a total of 32,834 patients who underwent F-FDG PET/CT, patients with focal uptake in the frontal process of the maxilla were selected by a database search. For those patients, medical records including relevant imaging studies were reviewed.

RESULTS

Thirty-nine patients (0.12 %) demonstrated focal uptake on PET/CT. On CT of PET/CT, all lesions showed ground-glass attenuation with or without bony expansion, consistent with fibrous dysplasia. When comparing previous PET/CT, follow-up PET/CT, and CT, a significant difference in degree of F-FDG uptake was noted, with no associated change in the size of maxillary lesions. There were no patients who had symptoms or signs related to maxillary lesions during follow-up.

CONCLUSION

Focal F-FDG uptake in the frontal process of the maxilla is a rare, incidental, and persistent finding with variable uptake and can represent a benign condition.

摘要

目的

我们研究了上颌骨额突偶然出现的局灶性氟代脱氧葡萄糖（F-FDG）摄取的患病率及其临床意义，这种摄取在正电子发射断层扫描/计算机断层扫描（PET/CT）上类似恶性病变。

方法

通过数据库检索，从总共32834例接受F-FDG PET/CT检查的患者中，挑选出上颌骨额突有局灶性摄取的患者。对于这些患者，回顾了包括相关影像学检查在内的病历资料。

结果

39例患者（0.12%）在PET/CT上显示局灶性摄取。在PET/CT的计算机断层扫描（CT）图像上，所有病变均表现为磨玻璃样密度影，伴或不伴有骨质膨胀，符合骨纤维异常增殖症。对比既往PET/CT、随访PET/CT及CT图像，发现F-FDG摄取程度存在显著差异，而上颌骨病变大小无相关变化。随访期间，没有患者出现与上颌骨病变相关的症状或体征。