黑色素瘤中的关键微小RNA：一篇综述短文
Pivotal MicroRNAs in Melanoma: A Mini-Review.
作者信息
Deng Zhenjun, Hao Jingang, Lei Dongyun, He Yongjing, Lu Lechun, He Li
机构信息
Department of Dermatology, First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Kunming, 650032, Yunnan, China.
Department of Medicine Image, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
出版信息
Mol Diagn Ther. 2016 Oct;20(5):449-55. doi: 10.1007/s40291-016-0219-y.
Melanoma is a common skin cancer associated with ultraviolet light exposure and genetic variance. However, the etiology and molecular mechanisms of melanoma remain unknown. Recent studies have shown that microRNAs (miRNAs) can play key roles in the development and prognosis of this disease. In this study, we reviewed several pivotal miRNAs that may contribute to melanoma by involvement in the processes of invasion, migration, and metastasis of melanoma cells.
黑色素瘤是一种与紫外线暴露和基因变异相关的常见皮肤癌。然而，黑色素瘤的病因和分子机制仍不清楚。最近的研究表明，微小RNA（miRNA）在这种疾病的发生发展和预后中可能起关键作用。在本研究中，我们综述了几种关键的miRNA，它们可能通过参与黑色素瘤细胞的侵袭、迁移和转移过程而导致黑色素瘤。
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