Jamaati H, Baghaei P, Sharifianfard M, Emami H, Najmi K, Seifi S, Salimi B, Pourabdollah M, Kiani A, Hashemian M, Khosravi A
Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran E-mail :
Asian Pac J Cancer Prev. 2016;17(6):2877-81.
Lung cancer is one of the most common causes of death that is rising in many countries including Iran. This study aimed to determine the impact of factors on survival of lung cancer patients at a referral center of lung diseases in Tehran, Iran.
A retrospective study was conducted on adult lung cancer cases admitted to a referral center for lung diseases from 2011 to 2015. Multivariate analysis was performed to determine the risk factors for all-cause mortality.
Of a total 933 patients with lung cancer, 53.4% died, 49.3% of them at the hospital. Overall median follow-up time was 7 months. The most common histological type of cancer was adenocarcinoma with a 13 month median survival time. Age ≥55 and smoking remained significant for all-cause mortality on Cox analysis, whereas gender was not.
The survival of lung cancer patients is poor and the patients with history of smoking and age ≥55 are at increased risk of death. Having a large hospital-based registry provides a good measurement of prognostic statistics for lung cancer. Further investigations are necessary to establish reasons for mortality.
肺癌是包括伊朗在内的许多国家中最常见的死亡原因之一，且其发病率正在上升。本研究旨在确定伊朗德黑兰一家肺病转诊中心的诸多因素对肺癌患者生存的影响。
对2011年至2015年入住一家肺病转诊中心的成年肺癌病例进行回顾性研究。采用多变量分析来确定全因死亡率的危险因素。
在总共933例肺癌患者中，53.4%死亡，其中49.3%在医院死亡。总体中位随访时间为7个月。最常见的癌症组织学类型是腺癌，中位生存时间为13个月。在Cox分析中，年龄≥55岁和吸烟对全因死亡率仍有显著影响，而性别则无。
肺癌患者的生存率较低，有吸烟史且年龄≥55岁的患者死亡风险增加。基于大型医院的登记系统可为肺癌的预后统计提供良好的衡量标准。有必要进行进一步调查以确定死亡原因。
