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实验性心脏骤停期间主动脉内球囊反搏的血流动力学效应

Hemodynamic effects of the intra-aortic balloon pump during experimental cardiac arrest.

作者信息

Emerman C L, Pinchak A C, Hagen J F, Hancock D

机构信息

Department of Emergency Medicine, Cleveland Metropolitan General Hospital, OH 44109.

出版信息

Am J Emerg Med. 1989 Jul;7(4):378-83. doi: 10.1016/0735-6757(89)90042-9.

DOI:10.1016/0735-6757(89)90042-9
PMID:2735983
Abstract

The low flow states and limited coronary perfusion provided by conventional cardiopulmonary resuscitation (CPR) have prompted investigations into alternative, more invasive, methods of resuscitation. Previous case reports and limited animal evidence have suggested that the intra-aortic balloon pump (IABP) may have a role in resuscitation. We used a canine cardiac arrest model to study the hemodynamic effects of the IABP during closed-chest CPR. A sensor attached to the chest plate of a Thumper was used to time a Datascope Model 3520 ventricular assist console such that the balloon inflated on the upstroke and deflated on the downstroke of the Thumper. There was no increase in systolic blood pressure with the balloon pump. Diastolic blood pressure and coronary perfusion pressure were significantly higher with the IABP. Circulation times were shorter and end-tidal CO2 was higher with the IABP. It was concluded that the IABP improves hemodynamic parameters during experimental cardiac arrest.

摘要

传统心肺复苏术(CPR)所提供的低血流状态以及有限的冠状动脉灌注促使人们对替代性的、侵入性更强的复苏方法展开研究。先前的病例报告和有限的动物实验证据表明,主动脉内球囊反搏(IABP)可能在复苏中发挥作用。我们使用犬类心脏骤停模型来研究在闭胸心肺复苏期间主动脉内球囊反搏的血流动力学效应。将一个传感器连接到胸外按压机的胸板上,用于给Datascope 3520型心室辅助控制台计时,以使球囊在胸外按压机的上升冲程时充气,在下降冲程时放气。使用球囊反搏时收缩压没有升高。使用主动脉内球囊反搏时舒张压和冠状动脉灌注压显著更高。使用主动脉内球囊反搏时循环时间更短,呼气末二氧化碳水平更高。得出的结论是,在实验性心脏骤停期间,主动脉内球囊反搏可改善血流动力学参数。

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引用本文的文献

1
Intra-aortic and Intra-caval Balloon Pump Devices in Experimental Non-traumatic Cardiac Arrest and Cardiopulmonary Resuscitation.主动脉内和腔静脉球囊泵设备在实验性非创伤性心脏骤停和心肺复苏中的应用。
J Cardiovasc Transl Res. 2023 Aug;16(4):948-955. doi: 10.1007/s12265-022-10343-9. Epub 2022 Dec 8.