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工作温度会影响微波子宫内膜消融术后的结果吗?

Does the working temperature affect the outcome following microwave endometrial ablation?

作者信息

Harmon M, Kasbekar A V, Sinha A, Andrews V

机构信息

University Hospital Lewisham, London, SE13 6LH, UK.

Aintree University Hospital, Liverpool, L9 7AL, UK.

出版信息

Ir J Med Sci. 2017 May;186(2):399-401. doi: 10.1007/s11845-016-1475-x. Epub 2016 Jun 30.

DOI:10.1007/s11845-016-1475-x
PMID:27363423
Abstract

BACKGROUND

Menorrhagia is a common gynaecological complaint, with significant burden to both its sufferers and health service providers. The first line of treatment is usually medical/pharmaceutical although in some cases surgery is required. There are now a number of minimally invasive surgical techniques available that ablate the uterine lining and prevent the need for the removal of the uterus. Microwave endometrial ablation (MEA) is one of these techniques, and this paper investigates the effect of the working temperature on outcome.

METHODS

A retrospective case note review of women who underwent MEA between June 2000 and August 2004. All women had a hysteroscopy followed by MEA. The duration of the procedure and mean working temperature of the MEA treatment was calculated. Women were followed up 6-8 months after surgery.

FINDINGS

Two hundred and eleven women underwent the procedure, with an average duration of menorrhagia of 30 months prior to the procedure. Eighty-nine percent attended follow-up, 80 % were satisfied with the procedure and 40 % were amenorrhoeic. When the procedure was performed at higher working temperature within the manufacturers guidelines women were more likely to be amenorrhoeic (78.4 vs. 77.1 °C, p = 0.014).

CONCLUSION

MEA is more effective in treating menorrhagia when used at a higher operating temperature.

摘要

背景

月经过多是一种常见的妇科病症,给患者和医疗服务提供者都带来了沉重负担。一线治疗通常是药物治疗,不过在某些情况下需要进行手术。现在有多种微创外科技术可用于消融子宫内膜,从而避免子宫切除。微波子宫内膜消融术(MEA)就是其中一种技术,本文研究了工作温度对治疗结果的影响。

方法

对2000年6月至2004年8月期间接受MEA治疗的女性进行回顾性病例记录审查。所有女性均先接受宫腔镜检查,然后进行MEA。计算手术时长和MEA治疗的平均工作温度。术后对女性进行6 - 8个月的随访。

结果

211名女性接受了该手术,术前平均月经过多持续时间为30个月。89%的患者接受了随访,80%对手术满意,40%出现闭经。当在制造商指南规定的较高工作温度下进行手术时,女性更有可能出现闭经(78.4对77.1°C,p = 0.014)。

结论

MEA在较高工作温度下用于治疗月经过多时效果更佳。

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本文引用的文献

1
Office endometrial ablation with local anesthesia using the HydroThermAblator system: Comparison of outcomes in patients with submucous myomas with those with normal cavities in 246 cases performed over 5(1/2) years.在 5 年半的时间里,对 246 例患者进行了局部麻醉下的 HydroThermAblator 系统宫腔镜子宫内膜切除术:比较黏膜下肌瘤患者与正常宫腔患者的结局。
J Minim Invasive Gynecol. 2009 Nov-Dec;16(6):700-7. doi: 10.1016/j.jmig.2009.06.023.
2
Diagnosis and treatment of menorrhagia.月经过多的诊断与治疗。
Acta Obstet Gynecol Scand. 2007;86(6):749-57. doi: 10.1080/00016340701415400.
3
Microwave endometrial ablation for menorrhagia: outcome at 2 years--experience of a district general hospital.
微波子宫内膜切除术治疗月经过多:2年随访结果——一家区综合医院的经验
J Obstet Gynaecol. 2004 Nov;24(8):916-9. doi: 10.1080/01443610400019005.
4
Microwave endometrial ablation vs. rollerball electroablation for menorrhagia: a multicenter randomized trial.
J Am Assoc Gynecol Laparosc. 2004 Aug;11(3):394-403. doi: 10.1016/s1074-3804(05)60057-6.
5
A heat transfer model of thermal balloon endometrial ablation.热球囊子宫内膜消融术的传热模型
Ann Biomed Eng. 2001 Nov;29(11):1009-18. doi: 10.1114/1.1415521.
6
Microwave endometrial ablation: development, clinical trials and outcomes at three years.
Br J Obstet Gynaecol. 1999 Jul;106(7):684-94. doi: 10.1111/j.1471-0528.1999.tb08368.x.