一名14岁男孩的重症副球孢子菌病
Severe Paracoccidioidomycosis in a 14-Year-Old Boy.
作者信息
Ruas L P, Pereira R M, Braga F G, Lima X T, Mamoni R L, Cintra M L, Schreiber A Z, Calich V L G, Blotta M H S L
机构信息
Department of Clinical Pathology, School of Medical Sciences, State University of Campinas (UNICAMP), Rua Tessalia Vieira de Camargo, 126, Campinas, São Paulo, 13083-878, Brazil.
Department of Pediatrics, School of Medical Sciences, State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
出版信息
Mycopathologia. 2016 Dec;181(11-12):915-920. doi: 10.1007/s11046-016-0035-2. Epub 2016 Jun 30.
Paracoccidioidomycosis (PCM) is the most important systemic mycoses in Latin America. We describe a severe case of paracoccidioidomycosis in a 14-year-old boy, with a rapid disease progression. The fungal strain was isolated and inoculated into a T and/or B cell immunocompromised mice, which revealed a highly virulent strain. The case report presented herein emphasizes the importance of considering PCM in the differential diagnosis of patients with other infectious diseases in endemic areas and highlights a novel isolate.
副球孢子菌病（PCM）是拉丁美洲最重要的系统性真菌病。我们描述了一名14岁男孩患严重副球孢子菌病的病例，疾病进展迅速。分离出真菌菌株并接种到T和/或B细胞免疫受损小鼠体内，结果显示该菌株具有高度毒性。本文呈现的病例报告强调了在流行地区对患有其他传染病的患者进行鉴别诊断时考虑PCM的重要性，并突出了一种新的分离株。
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